The large yellow croaker, Larimichthys crocea, is one of the most economically important marine fish species endemic to China. Its wild stocks have severely suffered from overfishing, and the aquacultured species are vulnerable to various marine pathogens. Here we report the creation of a draft genome of a wild large yellow croaker using a whole-genome sequencing strategy. We estimate the genome size to be 728 Mb with 19,362 protein-coding genes. Phylogenetic analysis shows that the stickleback is most closely related to the large yellow croaker. Rapidly evolving genes under positive selection are significantly enriched in pathways related to innate immunity. We also confirm the existence of several genes and identify the expansion of gene families that are important for innate immunity. Our results may reflect a well-developed innate immune system in the large yellow croaker, which could aid in the development of wild resource preservation and mariculture strategies.
[1]Zhejiang Ocean Univ, Natl Engn Res Ctr, Marine Facil Aquaculture, Zhoushan 316022, Peoples R China;
[2]Shanghai Jiao Tong Univ, Bio X Ctr, Key Lab Genet Dev & Neuropsychiat Disorders, Minist Educ, Shanghai 200030, Peoples R China;
[3]Chinese Acad Sci, Grad Sch, Shanghai Inst Biol Sci, Inst Nutr Sci, Shanghai 200031, Peoples R China;
[4]Xiamen Univ, Coll Ocean & Earth Sci, Xiamen 361005, Peoples R China;
[5]Fudan Univ, Inst Biomed Sci, Shanghai 200032, Peoples R China;
[6]ShanghaiBio Corp, N Brunswick, NJ 08902 USA
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