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Isolation and identification of a novel cDNA that encodes human yrdC protein  期刊论文  

  • 编号:
    1d5c2fac-13cc-4b2a-bbed-e64495d65740
  • 作者:
    Chen, Jinzhong[0][1] Ji, Chaoneng[1][1] Gu, Shaohua[2][2] Zhao, Enpeng[3][3] Dai, Jianliang[4][4] Huang, Lu[5][5] Qian, Ji[6][6] Ying, Kang[7][1] Xie, Yi[8][1] Mao, Yümin[9][1]
  • 地址:

    [1]Fudan University, Institute of Genetics,Shanghai,China

    [2]Fudan University, State Key Laboratory of Genetic Engineering and MOE Key Laboratory of Contemporary Anthropology,Shanghai,China

    [3]Marion Bessin Liver Research Center, Department of Medicine,New York,United States

    [4]Fudan University,Shanghai,China

    [5]Fudan University, School of Life Sciences,Shanghai,China

    [6]Fudan University School of Life Sciences, Institute of Genetics,Shanghai,China

  • Scopus被引频次:
    11 次
  • 语种:
    英文
  • 期刊:
    Journal of Human Genetics ISSN:1434-5161 2003 年 48 卷 4 期 (164 - 169)
  • 收录:
  • 关键词:
  • 摘要:

    In the course of detecting the interaction protein of RBBP10 by yeast two-hybridization, we isolated a novel cDNA that encodes a putative human protein with yrdC domain. It is named human yrdC protein. Because the cDNA contains an open reading fragment (ORF) without a 5′ in- frame stop codon, 5′ RACE and 3′ RACE were proceeded to produce the full-length cDNA. An 1825 bp cDNA was isolated from human placenta, which encodes a putative protein of 279 amino acids. The protein contains a sua5-yciO-yrdC domain. Blast analysis against the human genome database of Genbank revealed that the gene contains five exons, and assigned the gene to human chromosome 1p34.2. A transcript about 2.5 kb is ubiquitously expressed in human tissues. The gene is highly conserved during evolution.

  • 推荐引用方式
    GB/T 7714:
    Chen Jinzhong/35791589300[0],Ji Chaoneng/7202014188[1],Gu Shaohua/7202220494[2], et al. Isolation and identification of a novel cDNA that encodes human yrdC protein [J].Journal of Human Genetics,2003,48(4):164-169.
  • APA:
    Chen Jinzhong/35791589300[0],Ji Chaoneng/7202014188[1],Gu Shaohua/7202220494[2],Zhao Enpeng/7101850076[3],&Mao Yümin/7401999722[9].(2003).Isolation and identification of a novel cDNA that encodes human yrdC protein .Journal of Human Genetics,48(4):164-169.
  • MLA:
    Chen Jinzhong/35791589300[0], et al. "Isolation and identification of a novel cDNA that encodes human yrdC protein" .Journal of Human Genetics 48,4(2003):164-169.
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