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Organocatalytic enantioselective Michael addition of cyclic hemiacetals to nitroolefins: a facile access to chiral substituted 5-and 6-membered cyclic ethers  期刊论文  

  • 编号:
    1f5fa67b-b6bc-45b6-8af2-48059dbfee94
  • 作者:
    Zhu, Yadong[1,2];Qian, Pengfei[1,2];Yang, Jiyang[1,2];Chen, Shaohua[1,2];Hu, Yanwei[1,2];Wu, Ping[3];Wang, Wei[4];Zhang, Wei(张伟)[3]Zhang, Shilei[1,2];
  • 语种:
    English
  • 期刊:
    ORGANIC & BIOMOLECULAR CHEMISTRY ISSN:1477-0520 2015 年 13 卷 16 期 (4769 - 4775)
  • 收录:
  • 摘要:

    An efficient aminocatalytic enantioselective Michael addition of readily available cyclic hemiacetals to nitroolefins has been developed. The strategy serves as a powerful approach to synthetically valuable chiral 3-substituted tetrahydrofurans (THFs) and tetrahydropyrans (THPs). The synthetic utilities of the versatile Michael adducts also have been demonstrated in the synthesis of 2,3-disubstituted cyclic ethers, a-substituted lactones and venlafaxine analogues.

  • 推荐引用方式
    GB/T 7714:
    Zhu Yadong,Qian Pengfei,Yang Jiyang, et al. Organocatalytic enantioselective Michael addition of cyclic hemiacetals to nitroolefins: a facile access to chiral substituted 5-and 6-membered cyclic ethers [J].ORGANIC & BIOMOLECULAR CHEMISTRY,2015,13(16):4769-4775.
  • APA:
    Zhu Yadong,Qian Pengfei,Yang Jiyang,Chen Shaohua,&Zhang Shilei.(2015).Organocatalytic enantioselective Michael addition of cyclic hemiacetals to nitroolefins: a facile access to chiral substituted 5-and 6-membered cyclic ethers .ORGANIC & BIOMOLECULAR CHEMISTRY,13(16):4769-4775.
  • MLA:
    Zhu Yadong, et al. "Organocatalytic enantioselective Michael addition of cyclic hemiacetals to nitroolefins: a facile access to chiral substituted 5-and 6-membered cyclic ethers" .ORGANIC & BIOMOLECULAR CHEMISTRY 13,16(2015):4769-4775.
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