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The prevalence of plasmid-mediated quinolone resistance determinants among clinical isolates of ESBL or AmpC-producing Escherichia coli from Chinese pediatric patients 期刊论文

编号：

203d120f-d925-4f96-8721-0b310330a624
作者：

Han, Chenxi^[1] Yang, Yonghong^[1] Wang, Minggui^[2] Wang, Aihua^[1] Lu, Quan^[3] Xu, Xiwei^[1] Wang, Chuanqing^[4] Liu, Lan^[5] Deng, Qiulian^[6] Shen, Xuzhuang^[1]
语种：

English
期刊：

MICROBIOLOGY AND IMMUNOLOGY ISSN：0385-5600 2010 年 54 卷 3 期 (123 - 128) ; MAR
收录：
关键词：

ESBL or AmpC-producing Escherichia coli Pediatrics PMQR quinolone resistance
摘要：

Three kinds of PMQR determinants (qnr genes, aac(6')-Ib-cr, and qepA) have been discovered and shown to be widely distributed among clinical isolates. To characterize the prevalence of PMQR determinants in ESBL or AmpC-producing E. coli clinical isolates in Chinese children, a total of 292 ESBL or AmpC-producing E. coli clinical isolates collected from five children's hospitals in China from 2005 to 2006 were screened for PMQR determinants by PCR. Twenty (6.8%) of the 292 isolates were positive for PMQR determinants. A total of 12 (4.1%) isolates were positive for qnr genes, comprising three positive for qnrA (1.0%), three for qnrB (1.0%), and six for qnrS (2.1%). Twenty-four (8.2%) isolates were positive for aac(6')-Ib, of which 10 (3.4% of 292) had the -cr variant. There was no qepA gene detected in the isolates. Conjugation revealed that qnr, aac(6')-Ib-cr, and ESBL-encoding genes were transferred together.
推荐引用方式
GB/T 7714：

Han Chenxi,Yang Yonghong,Wang Minggui, et al. The prevalence of plasmid-mediated quinolone resistance determinants among clinical isolates of ESBL or AmpC-producing Escherichia coli from Chinese pediatric patients [J].MICROBIOLOGY AND IMMUNOLOGY,2010,54(3):123-128.
APA：

Han Chenxi,Yang Yonghong,Wang Minggui,Wang Aihua,&Shen Xuzhuang.(2010).The prevalence of plasmid-mediated quinolone resistance determinants among clinical isolates of ESBL or AmpC-producing Escherichia coli from Chinese pediatric patients .MICROBIOLOGY AND IMMUNOLOGY,54(3):123-128.
MLA：

Han Chenxi, et al. "The prevalence of plasmid-mediated quinolone resistance determinants among clinical isolates of ESBL or AmpC-producing Escherichia coli from Chinese pediatric patients" .MICROBIOLOGY AND IMMUNOLOGY 54,3(2010):123-128.

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