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New superporous hydrogels composites based on aqueous Carbopol((R)) solution (SPHCcs): synthesis, characterization and in vitro bioadhesive force studies 期刊论文

编号：

21c7285b-fb90-483c-839e-79437c93491b
作者：

Tang, C; Yin, CH; Pei, YY; Zhang, M; Wu, LF
语种：

English
期刊：

EUROPEAN POLYMER JOURNAL ISSN：0014-3057 2005 年 41 卷 3 期 (557 - 562) ; MAR
收录：
关键词：

superporous hydrogel composite Carbopol((R)) swelling mucoadhesion
摘要：

In this investigation new superporous hydrogels composites based on aqueous Carbopol((R)) solution (SPHCcs) were prepared. SEM images indicated that the inner surface of SPHCcs contained a lot of pores connected each other and the outer surface of them was non-porous. The swelling ratio decreased with increasing the content of aqueous Carbopolo solution, and the final swelling ratio was similar to that of the SPH although the initial swelling ratio was lower. The density measurement revealed that the porosity increased when aqueous Carbopolo solution was incorporated. It was observed from in vitro bioadhesive force study that SPHCcs adhered to the intestinal mucosal more quickly and exhibited higher mucoadhesion as compared with SPH. It is evident that the hydrogels synthesized in this study could be a potential candidate for transmucosal drug delivery system. (C) 2004 Elsevier Ltd. All rights reserved.
推荐引用方式
GB/T 7714：

Tang C,Yin CH,Pei YY, et al. New superporous hydrogels composites based on aqueous Carbopol((R)) solution (SPHCcs): synthesis, characterization and in vitro bioadhesive force studies [J].EUROPEAN POLYMER JOURNAL,2005,41(3):557-562.
APA：

Tang C,Yin CH,Pei YY,Zhang M,&Wu LF.(2005).New superporous hydrogels composites based on aqueous Carbopol((R)) solution (SPHCcs): synthesis, characterization and in vitro bioadhesive force studies .EUROPEAN POLYMER JOURNAL,41(3):557-562.
MLA：

Tang C, et al. "New superporous hydrogels composites based on aqueous Carbopol((R)) solution (SPHCcs): synthesis, characterization and in vitro bioadhesive force studies" .EUROPEAN POLYMER JOURNAL 41,3(2005):557-562.

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