首页 / 院系成果 / 成果详情页

Evaluation of transient elastography in assessing liver fibrosis in patients with advanced schistosomiasis japonica 期刊论文

编号：

24e745ab-6a51-4a15-98d0-9e8d320a8a66
作者：

Wu, Shengdi(吴盛迪)#^[1,2]Tseng, Yujen^[1];Xu, Nuo(许诺)^[3]Yin, Xinguang^[4];Xie, Xinsheng^[4];Zhang, Lifang^[5];Wu, Wanxin^[6];Zhu, Wenjun^[7];Wu, Wenlin^[5];Yao, Jiankang^[8];Wu, Yiming^[4,5];
语种：

英文
期刊：

PARASITOLOGY INTERNATIONAL ISSN：1383-5769 2018 年 67 卷 3 期 (302 - 308) ; JUN
收录：
关键词：

Liver stiffness measurement Transient elastography Liver fibrosis Advanced schistosomiasis japonica Noninvasive
摘要：

Schistosomiasis remains an important public health issue. The presence and extent of liver fibrosis are associated with disease progression and prognosis. The study is aimed at exploring the value of liver stiffness measurement (LSM) by transient elastography in assessing liver fibrosis in patients with advanced schistosomiasis japonica. Seventy-three patients were consecutively recruited for the purpose of this study. The correlation between noninvasive parameters and histological fibrosis stages was analyzed and an area under receiver operating characteristic curve (AUROC) was used to assess diagnostic efficacy. Our results demonstrated that there are significant differences between LSM values of patients with different stages of fibrosis (F1 vs. F2, F2 vs. F3 and F3 vs. F4, P < 0.01). The AUROC values of LSM in detecting significant fibrosis (F >= 2), advanced fibrosis (F >= 3) and cirrhosis (F = 4) were 0.96, 0.90, and 0.92 respectively. The optimal cut-off ISM values were 8.0 kPa, 9.5 kPa, and 18.0 kPa for significant fibrosis, advanced fibrosis and cirrhosis. Based on differences between AUROC values, LSM was proven to be superior to several serum models in detecting advanced fibrosis and cirrhosis. In conclusion, our study demonstrates that LSM is a reliable parameter for assessing risk of liver fibrosis in patients with advanced schistosomiasis japonica.
推荐引用方式
GB/T 7714：

Wu Shengdi,Tseng Yujen,Xu Nuo, et al. Evaluation of transient elastography in assessing liver fibrosis in patients with advanced schistosomiasis japonica [J].PARASITOLOGY INTERNATIONAL,2018,67(3):302-308.
APA：

Wu Shengdi,Tseng Yujen,Xu Nuo,Yin Xinguang,&Wu Yiming.(2018).Evaluation of transient elastography in assessing liver fibrosis in patients with advanced schistosomiasis japonica .PARASITOLOGY INTERNATIONAL,67(3):302-308.
MLA：

Wu Shengdi, et al. "Evaluation of transient elastography in assessing liver fibrosis in patients with advanced schistosomiasis japonica" .PARASITOLOGY INTERNATIONAL 67,3(2018):302-308.
条目包含文件：

文件类型：PDF,文件大小：

正在加载全文

未找到全文

浏览次数：11  下载次数：0

分享到：

浏览次数：11

下载次数：0

打印次数：0