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Improving Detection of Iron Deposition in Cirrhotic Liver Using Susceptibility-Weighted Imaging With Emphasis on Histopathological Correlation 期刊论文

编号：

27abca23-7e5e-4759-aa19-415393208a86
作者：

Li, RuoKun(李若坤)^[1,2]Zeng, MengSu^[3];Qiang, JinWei^[2];Palmer, Suzanne L.^[4];Chen, Frank^[4];Rao, ShengXiang^[3];Chen, LingLi(陈伶俐)^[5]Dai, YongMing^[6];
语种：

English
期刊：

JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY ISSN：0363-8715 2017 年 41 卷 1 期 (18 - 24) ; JAN
收录：
关键词：

iron deposition cirrhosis susceptibility-weighted imaging magnetic resonance imaging pathology
摘要：

Objective: The aim of this study was to investigate the value of susceptibility-weighted imaging (SWI) for detection and quantification of iron deposition in cirrhotic liver. Methods: Fifty-five cirrhotic patients underwent hepatic magnetic resonance imaging examination including SWI and multiecho T2*-weighted imaging (T2*WI). Detection of iron deposition and number of siderotic nodules were compared between SWI and T2*WI. Correlation among SWI phase value, T2*value, and hepatic iron concentration were determined. Results: Susceptibility-weighted imaging significantly improved detection of iron deposition compared with T2*WI (90.7% vs 66.7%, P = 0.002), attributing to grade 1 (73.3% vs 26.7%, P = 0.027) and grade 2 (93.8% vs 56.3%, P = 0.037). Iron deposition of grade 3 and 4 could be detected by both SWI and T2*WI. The number of siderotic nodules visualized on SWI was significantly larger than that on T2*WI (107.5 +/- 7.4 vs 62.7 +/- 4.6, P = 0.002). There were significantly negative correlation between phase value and iron score (r = -0.803), and positive correlation between phase value and T2*value (r = 0.771). Conclusions: Susceptibility-weighted imaging can improve detection of minimal and mild iron deposition in cirrhotic liver.
推荐引用方式
GB/T 7714：

Li Ruo-Kun,Zeng Meng-Su,Qiang Jin-Wei, et al. Improving Detection of Iron Deposition in Cirrhotic Liver Using Susceptibility-Weighted Imaging With Emphasis on Histopathological Correlation [J].JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY,2017,41(1):18-24.
APA：

Li Ruo-Kun,Zeng Meng-Su,Qiang Jin-Wei,Palmer Suzanne L.,&Dai Yong-Ming.(2017).Improving Detection of Iron Deposition in Cirrhotic Liver Using Susceptibility-Weighted Imaging With Emphasis on Histopathological Correlation .JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY,41(1):18-24.
MLA：

Li Ruo-Kun, et al. "Improving Detection of Iron Deposition in Cirrhotic Liver Using Susceptibility-Weighted Imaging With Emphasis on Histopathological Correlation" .JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY 41,1(2017):18-24.

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