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Weighted Rank Tests for Noninferiority Hypotheses Based on Paired Survival Times  期刊论文  

  • 编号:
    2a664b70-1721-4b8d-b000-17874acf9611
  • 作者:
  • 语种:
    English
  • 期刊:
    JOURNAL OF BIOPHARMACEUTICAL STATISTICS ISSN:1054-3406 2013 年 23 卷 2 期 (432 - 446) ; MAR 11
  • 收录:
  • 关键词:
  • 摘要:

    Motivated by the design and analysis of a specific type of Phase II cancer clinical trials, we derive in this article a class of weighted rank tests for the testing of noninferiority hypotheses with a prespecified margin based on paired survival times. Monte Carlo simulations are performed to evaluate the performance of the proposed tests. Sample size calculation when these tests are used for the analysis is also discussed. Procedures developed are also applied to a Phase II clinical trial of metastatic breast cancer.

  • 推荐引用方式
    GB/T 7714:
    Jin Huan,Zhao Naiqing,Tu Dongsheng, et al. Weighted Rank Tests for Noninferiority Hypotheses Based on Paired Survival Times [J].JOURNAL OF BIOPHARMACEUTICAL STATISTICS,2013,23(2):432-446.
  • APA:
    Jin Huan,Zhao Naiqing,Tu Dongsheng.(2013).Weighted Rank Tests for Noninferiority Hypotheses Based on Paired Survival Times .JOURNAL OF BIOPHARMACEUTICAL STATISTICS,23(2):432-446.
  • MLA:
    Jin Huan, et al. "Weighted Rank Tests for Noninferiority Hypotheses Based on Paired Survival Times" .JOURNAL OF BIOPHARMACEUTICAL STATISTICS 23,2(2013):432-446.
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