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Synthetic studies on coenzyme Q<inf>10</inf>: Part 2 - A efficient and improved synthesis of coenzyme Q<inf>10</inf> via the C<inf>5</inf> + C <inf>45</inf> approach  期刊论文  

  • 编号:
    2b2fe9e1-32d4-43d2-85d2-3bd73bad4c4e
  • 作者:
    Dai, Huifang[0](戴惠芳)#[1]Chen, Fener[1][2];Yu, Xiongjie[2][2];
  • 地址:

    [1]Fudan University, School of Pharmacy,Shanghai,China

    [2]Fudan University, Department of Chemistry,Shanghai,China

  • Scopus被引频次:
    6 次
  • 语种:
    英文
  • 期刊:
    Helvetica Chimica Acta ISSN:0018-019X 2006 年 89 卷 7 期 (1317 - 1321)
  • 收录:
  • 摘要:

    An improved route to coenzyme Q10 (1) starting from commercially available coenzyme Q1 is described. The key steps in this synthesis are the SeO2-mediated oxidation of the protected isoprenylhydroquinone 3 into the (E)-allyl alcohol 5 without the formation of undesired stereoisomer and the one-pot reductive elimination of the phenylsulfonyl and dibenzyl groups in 7 by using naphthalenyllithium. © 2006 Verlag Helvetica Chimica Acta AG.

  • 推荐引用方式
    GB/T 7714:
    Dai Huifang/16204810500[0],Chen Fener/7404907528[1],Yu Xiongjie/7404115711[2], et al. Synthetic studies on coenzyme Q10: Part 2 - A efficient and improved synthesis of coenzyme Q10 via the C5 + C 45 approach [J].Helvetica Chimica Acta,2006,89(7):1317-1321.
  • APA:
    Dai Huifang/16204810500[0],Chen Fener/7404907528[1],Yu Xiongjie/7404115711[2].(2006).Synthetic studies on coenzyme Q10: Part 2 - A efficient and improved synthesis of coenzyme Q10 via the C5 + C 45 approach .Helvetica Chimica Acta,89(7):1317-1321.
  • MLA:
    Dai Huifang/16204810500[0], et al. "Synthetic studies on coenzyme Q10: Part 2 - A efficient and improved synthesis of coenzyme Q10 via the C5 + C 45 approach" .Helvetica Chimica Acta 89,7(2006):1317-1321.
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