首页 / 院系成果 / 成果详情页

Early detection of anthracycline-induced cardiotoxicity using two-dimensional speckle tracking echocardiography 期刊论文

编号：

2bad2772-de63-46e6-ac54-acf074e2f0b2
作者：

Kang, Yu^[1,2];Cheng, Leilei^[2];Li, Lin^[2];Chen, Haiyan^[2];Sun, Minmin^[2];Wei, Zheng(魏征)^[3]Pan, Cuizhen^[2];Shu, Xianhong^[2];
语种：

English
期刊：

CARDIOLOGY JOURNAL ISSN：1897-5593 2013 年 20 卷 6 期 (592 - 599)
收录：
关键词：

two-dimensional speckle tracking echocardiography anthracycline-induced cardiotoxicity left ventricular systolic function
摘要：

Background: To examine the subclinical myocardial injury shortly after epirubicin exposure in asymptomatic patients with large B-cell non-Hodgkin lymphoma using 2-dimensional (2D) speckle tracking echocardiography. Methods: Sixty-seven patients aged 52.58 +/- 13.86 years with large B-cell non-Hodgkin lymphoma treated with epirubicin were studied. Echocardiography was performed at baseline and 1 day after completion of the therapy. Global and regional longitudinal (LS), circumferential (CS) and radial strain (RS), standard deviation of time to peak LS (TLS-SD), CS (TCS-SD), RS (TRS-SD) were calculated using 2D speckle tracking echocardiography. Results: Despite normal left ventricular ejection fraction, global LS (-18.30 +/- 1.87% vs. -16.18 +/- 1.92%; p < 0.01), CS (-20.37 +/- 2.89% vs. -18.25 +/- 2.40%, p < 0.01) and RS (39.95 +/- 5.79% vs. 36.15 +/- 5.79%, p < 0.01), were remarkably reduced compared to baseline values. However, TLS-SD, TCS-SD and TRS-SD showed no significant difference after epirubicin exposure. Hypertension was an independent predictor of reduction of global LS, CS and RS. Conclusions: Subtle abnormalities in myocardial systolic function were present in asymptomatic patients shortly after anthracycline exposure, which could be detected by 2D speckle tracking echocardiography.
推荐引用方式
GB/T 7714：

Kang Yu,Cheng Leilei,Li Lin, et al. Early detection of anthracycline-induced cardiotoxicity using two-dimensional speckle tracking echocardiography [J].CARDIOLOGY JOURNAL,2013,20(6):592-599.
APA：

Kang Yu,Cheng Leilei,Li Lin,Chen Haiyan,&Shu Xianhong.(2013).Early detection of anthracycline-induced cardiotoxicity using two-dimensional speckle tracking echocardiography .CARDIOLOGY JOURNAL,20(6):592-599.
MLA：

Kang Yu, et al. "Early detection of anthracycline-induced cardiotoxicity using two-dimensional speckle tracking echocardiography" .CARDIOLOGY JOURNAL 20,6(2013):592-599.

浏览次数：4  下载次数：0

分享到：

浏览次数：4

下载次数：0

打印次数：0