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Adverse childhood experiences and interaction with methamphetamine use frequency in the risk of methamphetamine-associated psychosis  期刊论文  

  • 编号:
    2c2c0751-d98d-4c71-9ace-0b6157310737
  • 作者:
    Ding, Yingying(丁盈盈)#[1,2]Lin, Haijiang[3];Zhou, Lin[1,2];Yan, Huamei[1,2];He, Na(何纳)*[1,2,4]
  • 语种:
    English
  • 期刊:
    DRUG AND ALCOHOL DEPENDENCE ISSN:0376-8716 2014 年 142 卷 (295 - 300) ; SEP 1
  • 收录:
  • 关键词:
  • 摘要:

    Background: This study aims to examine adverse childhood experiences (ACEs), its interaction with methamphetamine (METH) use (e.g., frequency, duration, and dependence) and METH-associated risk of psychosis. Methods: This was a cross-sectional study conducted among METH users at a drug rehabilitation center in China. Participants were assessed using Mini International Neuropsychiatric Interview for METH-associated psychosis. Results: Of 189 participants, 50.5% reported at least one of eight ACE categories and 35.4% had past history of a psychotic episode. After adjusting for age, sex, education, and marital status, all ACE categories except emotional abuse and parental separation or divorce increased the risk of ever experiencing METH-associated psychosis. When comparing participants who reported no ACEs, those with three or more ACEs had higher risks of lifetime psychosis (OR = 4.5, 95% CI: 1.6-12.6). Relationship between number of ACEs and lifetime psychosis was graded (p < .01). The interaction between frequency of METH use (>= 4 vs. <4 times/month) and number of ACEs on the risk of METH-associated psychosis was statistically significant (p = 0.02), showing a trend of adjusted OR decreased significantly as the number of ACEs increased. Conclusions: These analyses indicate that childhood adversities increase the individual's vulnerability to METH-associated psychosis. Further larger longitudinal studies are warranted. (C) 2014 Elsevier Ireland Ltd. All rights reserved.

  • 推荐引用方式
    GB/T 7714:
    Ding Yingying,Lin Haijiang,Zhou Lin, et al. Adverse childhood experiences and interaction with methamphetamine use frequency in the risk of methamphetamine-associated psychosis [J].DRUG AND ALCOHOL DEPENDENCE,2014,142:295-300.
  • APA:
    Ding Yingying,Lin Haijiang,Zhou Lin,Yan Huamei,&He Na.(2014).Adverse childhood experiences and interaction with methamphetamine use frequency in the risk of methamphetamine-associated psychosis .DRUG AND ALCOHOL DEPENDENCE,142:295-300.
  • MLA:
    Ding Yingying, et al. "Adverse childhood experiences and interaction with methamphetamine use frequency in the risk of methamphetamine-associated psychosis" .DRUG AND ALCOHOL DEPENDENCE 142(2014):295-300.
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