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Flow diverter effect of LVIS stent on cerebral aneurysm hemodynamics: a comparison with Enterprise stents and the Pipeline device 期刊论文

编号：

2f51d82e-cb74-4d60-90d1-a1fee39c666a
作者：

Wang, Chao^[1,2,3] Tian, Zhongbin^[1,2] Liu, Jian^[1,2] Jing, Linkai^[1,2] Paliwal, Nikhil^[4,5] Wang, Shengzhang^[6] Zhang, Ying^[1,2] Xiang, Jianping^[4,5] Siddiqui, Adnan H.^[4,7] Meng, Hui^[4,5] Yang, Xinjian^[1,2]
语种：

English
期刊：

JOURNAL OF TRANSLATIONAL MEDICINE ISSN：1479-5876 2016 年 14 卷 ; JUL 2
收录：
关键词：

Computational fluid dynamics (CFD) Wall shear stress (WSS) Intracranial aneurysm LVIS Hemodynamics
摘要：

Background: The aim of this study was to quantify the effect of the new Low-profile Visualized Intraluminal Support (LVIS (R) D) device and the difference of fluid diverting effect compared with the Pipeline device and the Enterprise stent using computational fluid dynamics (CFD). Methods: In this research, we simulated three aneurysms constructed from 3D digital subtraction angiography (DSA). The Enterprise, LVIS and the Pipeline device were virtually conformed to fit into the vessel lumen and placed across the aneurysm orifice. Computational fluid dynamics analysis was performed to compare the hemodynamic differences such as WSS, Velocity and Pressure among these stents. Results: Control referred to the unstented model, the percentage of hemodynamic changes were all compared to Control. A single LVIS stent caused more wall shear stress reduction than double Enterprise stents (39.96 vs. 30.51 %) and velocity (23.13 vs. 18.64 %). Significant reduction in wall shear stress (63.88 %) and velocity (46.05 %) was observed in the double-LVIS stents. A single Pipeline showed less reduction in WSS (51.08 %) and velocity (37.87 %) compared with double-LVIS stent. The double-Pipeline stents resulted in the most reduction in WSS (72.37 %) and velocity (54.26 %). Moreover, the pressure increased with minuscule extent after stenting, compared with the unstented model. Conclusions: This is the first study analyzing flow modifications associated with LVIS stents. We found that the LVIS stent has certain hemodynamic effects on cerebral aneurysms: a single LVIS stent caused more flow reductions than the double-Enterprise stent but less than a Pipeline device. Nevertheless, the double-LVIS stent resulted in a better flow diverting effect than a Pipeline device.
推荐引用方式
GB/T 7714：

Wang Chao,Tian Zhongbin,Liu Jian, et al. Flow diverter effect of LVIS stent on cerebral aneurysm hemodynamics: a comparison with Enterprise stents and the Pipeline device [J].JOURNAL OF TRANSLATIONAL MEDICINE,2016,14.
APA：

Wang Chao,Tian Zhongbin,Liu Jian,Jing Linkai,&Yang Xinjian.(2016).Flow diverter effect of LVIS stent on cerebral aneurysm hemodynamics: a comparison with Enterprise stents and the Pipeline device .JOURNAL OF TRANSLATIONAL MEDICINE,14.
MLA：

Wang Chao, et al. "Flow diverter effect of LVIS stent on cerebral aneurysm hemodynamics: a comparison with Enterprise stents and the Pipeline device" .JOURNAL OF TRANSLATIONAL MEDICINE 14(2016).

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