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Clinical outcomes and risk factors of coronary artery aneurysms after successful percutaneous coronary intervention and drug-eluting stent implantation for chronic total occlusions 期刊论文

编号：

31b01926-499a-464b-85c6-7733046bdbd4
作者：

Zhong, Xin[0]^[1];Li, Hua[1]^[2];Li, Chenguang[2]^[1];Zong, Nobel[3]^[3];Liem, David[4]^[4];Chan, Xavia[5]^[3];Zhang, Shuning[6]^[5];Zhang, Youen[7]^[1];Wang, Xinggang[8]^[6];Wu, Xing[9](吴惺)^[7]Zhang, Wenbin[10]^[8];Yao, Kang[11]^[9];Liu, Xuebo[12]^[10];Ge, Lei[13]^[11];Hu, Kai[14]^[12];Qian, Juying[15]^[11];Deng, Mario[16]^[13];Ge, Junbo[17](葛均波)^[1]
地址：

[1]Fudan University, Shanghai Institute of Cardiovascular Diseases,Shanghai,China
[2]Chinese Academy of Sciences, Institute of Biochemistry and Cell Biology,Beijing,China
[3]David Geffen School of Medicine at UCLA, Departments of Physiology and Medicine/CVRL,Los Angeles,United States
[4]UCLA David Geffen School of Medicine, Department of Physiology,,United States
[5]Fudan University Shanghai Medical College, Department of Cardiology,Shanghai,China
[6]Fudan University, Department of Cardiovascular Diseases,Shanghai,China
[7]Huashan Hospital, Department of Neurosurgery,Shanghai,China
[8]Zhejiang University, Department of Cardiology,Hangzhou,China
[9]Zhongshan Hospital Shanghai,Shanghai,China
[10]Tongji University, Department of Cardiovascular Medicine,Shanghai,China
[11]Fudan University, Department of Cardiology,Shanghai,China
[12]Julius-Maximilians-Universitat Wurzburg, Comprehensive Heart Failure Center,Wurzburg,Germany
[13]David Geffen School of Medicine at UCLA,Los Angeles,United States
语种：

英文
期刊：

IJC Heart and Vessels ISSN：2214-7632 2014 年 4 卷 1 期 (108 - 115)
收录：
关键词：

Chronic total coronary occlusion Coronary artery aneurysm Drug-eluting stent Ostial occlusion Parallel wire technique
摘要：

Objective: The study aimed to analyze the risk factors and long-term outcomes associated with coronary artery aneurysms (CAAs) after successful percutaneous coronary intervention (PCI) and drug-eluting stent (DES) implantation in patients with CTOs. Background: There are sporadic data available on post-procedure CAAs after transcatheter revascularization for CTOs. Methods and results: A total of 141 patients with 149 CTOs who underwent successful CTO-PCI and DES implantation with angiographic follow-up from 2004 to 2010 were included. Patients were divided into CAA group and non-CAA group according to the presence of CAAs in the follow-up angiography. The independent predictors and major adverse cardiac events (MACEs) including cardiac death, myocardial infarction (MI) and target-vessel revascularization (TVR) were compared between two groups. The incidence of CAAs was 11.4% (17/149) after index procedure. Multivariate analysis showed that age (OR: 0.925, CI 0.873-0.980, P = 0.008), ostial occlusion (OR: 6.715, CI 1.473-30.610, P = 0.014), the parallel wire technique (OR: 6.167, CI 1.709-22.259, P = 0.005) and DES length (OR: 1.030, CI 1.002-1.058, P = 0.036) were the independent predictors of CAAs after successful CTO-PCI and DES implantation. MACEs were similar between two groups (adjusted hazard ratio 0.670; 95% CI 0.160-2.808; P = 0.584) during the 5-year follow-up. Conclusions: The independent predictors of CAAs after successful CTO-PCI and DES implantation are age, ostial occlusion, the parallel wire technique and DES length. CAAs after index procedure are not frequently associated with adverse clinical events under dual antiplatelet therapy. Further large clinical studies are warranted to explore the clinical implications of patients with this distinct new entity. © 2014 The Authors. Published by Elsevier Ireland Ltd.
推荐引用方式
GB/T 7714：

Zhong Xin/54879886500[0],Li Hua/57187328200[1],Li Chenguang/56540126500[2], et al. Clinical outcomes and risk factors of coronary artery aneurysms after successful percutaneous coronary intervention and drug-eluting stent implantation for chronic total occlusions [J].IJC Heart and Vessels,2014,4(1):108-115.
APA：

Zhong Xin/54879886500[0],Li Hua/57187328200[1],Li Chenguang/56540126500[2],Zong Nobel/57190866708[3],&Ge Junbo/7202197226[17].(2014).Clinical outcomes and risk factors of coronary artery aneurysms after successful percutaneous coronary intervention and drug-eluting stent implantation for chronic total occlusions .IJC Heart and Vessels,4(1):108-115.
MLA：

Zhong Xin/54879886500[0], et al. "Clinical outcomes and risk factors of coronary artery aneurysms after successful percutaneous coronary intervention and drug-eluting stent implantation for chronic total occlusions" .IJC Heart and Vessels 4,1(2014):108-115.

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