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Differential prevalence and correlates of whole blood Epstein-Barr virus DNA between HIV-positive and HIV-negative men who have sex with men in Shanghai, China 期刊论文

编号：

320068d5-469d-4a16-bf1d-3f0b4398b8fb
作者：

Pan, R.^[1,2,3];Liu, X.(刘星)^[1,2]Zhou, S.^[1,2];Ning, Z.^[4];Zheng, H.^[5];Gao, M.^[1,2];Ding, Y.^[1,2];Yao, W.^[3];Liao, X.^[3];He, N.^[1,2];
语种：

English
期刊：

EPIDEMIOLOGY AND INFECTION ISSN：0950-2688 2017 年 145 卷 11 期 (2330 - 2340) ; AUG
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关键词：

Cancer EBV HIV MSM risk factors
摘要：

This cross-sectional study aimed to examine and compare prevalence and correlates of whole blood Epstein-Barr virus (EBV) DNA between HIV-positive and HIV-negative men who have sex with men (MSM). Five hundred and four HIV-positive MSM and 504 age-matched HIV-negative MSM were recruited from an HIV counseling and testing clinic in Shanghai, China from November 2014 to November 2015 and were administered with a face-to-face questionnaire interview. Whole blood EBV DNA was tested by nested polymerase chain reaction assays on EBNA-1, EBNA-2, and LMP-1 genes. The prevalence of whole blood EBV DNA was 56.0% (95% CI 51.7-60.3%) among HIV-positive MSM and 26.0% (95% CI 22.4-30.0%) among HIVnegative MSM. Whole blood EBV DNA positivity was significantly associated with HIV infection (adjusted odds ratio (aOR) 3.43, 95% CI 2.58-4.57) and frequent intake of pickled, smoked, or salty food (aOR 1.71, 95% CI 1.02-2.86) in the whole sample, and with <200 cells/mu l CD4 cell counts (aOR 1.79, 95% CI 1.05-3.05) and pickled, smoked, or salty food intake (aOR 3.14, 95% CI 1.39-7.08) in HIV-positive group. HIV-infected MSM are at higher risk of active EBV replication than HIV-uninfected MSM, underscoring needs of surveillance and research on EBV-related carcinogenesis in this population.
推荐引用方式
GB/T 7714：

Pan R.,Liu X.,Zhou S., et al. Differential prevalence and correlates of whole blood Epstein-Barr virus DNA between HIV-positive and HIV-negative men who have sex with men in Shanghai, China [J].EPIDEMIOLOGY AND INFECTION,2017,145(11):2330-2340.
APA：

Pan R.,Liu X.,Zhou S.,Ning Z.,&He N..(2017).Differential prevalence and correlates of whole blood Epstein-Barr virus DNA between HIV-positive and HIV-negative men who have sex with men in Shanghai, China .EPIDEMIOLOGY AND INFECTION,145(11):2330-2340.
MLA：

Pan R., et al. "Differential prevalence and correlates of whole blood Epstein-Barr virus DNA between HIV-positive and HIV-negative men who have sex with men in Shanghai, China" .EPIDEMIOLOGY AND INFECTION 145,11(2017):2330-2340.

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