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The association between polymorphisms of genes related to inflammation and recurrent pregnancy loss 期刊论文

编号：

4c8d02d8-c6eb-43b8-9fb9-323309ba5f81
作者：

Gu, Yan^[1] Wang, Jian Mei^[1] Zhang, Zhao Feng^[2] Wang, Jian^[2] Cao, Yun Lei^[2] Pan, Cai Jun^[1] Yin, Li Rong^[1] Du, Jing^[2]
语种：

English
期刊：

GYNECOLOGICAL ENDOCRINOLOGY ISSN：0951-3590 2018 年 34 卷 4 期 (349 - 352)
收录：
关键词：

Reproductive immunology genetics recurrent pregnancy loss
摘要：

Aim: Recurrent pregnancy loss (RPL) occurs in 1-2% of pregnant women and about 50% of RPL cases are unexplained. Previous studies have shown that genetic variation in immune response genes can contribute to the risk in pregnancy maintenance during pregnancy. The aim of the present study was to evaluate the relationship between RPL and genes those have previously been associated with an inflammatory process on 107 RPL cases and 187 healthy controls.Methods: In this work, the single-nucleotide polymorphisms was examined by utilizing the direct sequencing and the Sequenom MassARRAY system.Results: The FAU rs769440G allele had higher frequencies in patients with RPL (p=.019). No association was observed between other polymorphisms and RPL.Conclusion: The results showed an association between FAU rs769440 polymorphism and RPL in Chinese Han population.
推荐引用方式
GB/T 7714：

Gu Yan,Wang Jian Mei,Zhang Zhao Feng, et al. The association between polymorphisms of genes related to inflammation and recurrent pregnancy loss [J].GYNECOLOGICAL ENDOCRINOLOGY,2018,34(4):349-352.
APA：

Gu Yan,Wang Jian Mei,Zhang Zhao Feng,Wang Jian,&Du Jing.(2018).The association between polymorphisms of genes related to inflammation and recurrent pregnancy loss .GYNECOLOGICAL ENDOCRINOLOGY,34(4):349-352.
MLA：

Gu Yan, et al. "The association between polymorphisms of genes related to inflammation and recurrent pregnancy loss" .GYNECOLOGICAL ENDOCRINOLOGY 34,4(2018):349-352.

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