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Evaluation of a High Concentrated Contrast Media Injection Protocol in Combination with Low Tube Current for Dose Reduction in Coronary Computed Tomography Angiography: A Randomized, Two-center Prospective Study 期刊论文

编号：

4cd40d75-aaeb-453b-8a54-cce4373c1b97
作者：

Sun, Yibo^[1];Hua, Yanqing(滑炎卿)^[2]Wang, Mingpeng(王鸣鹏)^[2]Mao, Dingbiao(毛定飚)^[2]Jin, Xiu^[2];Li, Cheng(李骋)^[2]Shi, Kailei(史凯蕾)^[3]Xu, Jianrong^[1];
语种：

English
期刊：

ACADEMIC RADIOLOGY ISSN：1076-6332 2017 年 24 卷 12 期 (1482 - 1490) ; DEC
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关键词：

Dose reduction high concentration contrast media coronary computed tomography angiography mAs image quality
摘要：

Rationale and Objectives: The study aimed to prospectively evaluate the radiation dose reduction potential and image quality (IQ) of a high-concentration contrast media (HCCM) injection protocol in combination with a low tube current (mAs) in coronary computed tomography angiography. Materials and Methods: Eighty-one consecutive patients (mean age: 62 years; 34 females; body mass index: 18-31) were included and randomized-assigned into two groups. All computed tomography (CT) examinations were performed in two groups with the same tube voltage (100 kV), flow rate of contrast medium (5.0 mL/s), and iodine dose (22.8 g). An automatic mAs and low concentration contrast medium (300 mgl/mL) were used in group A, whereas effective mAs was reduced by a factor 0.6 along with HCCM (400 mgl/mL) in group B. Radiation dose was assessed (CT dose index [CTD1,01] and dose length product), and vessel-based objective IQ for various regions of interest (enhancement, noise, signal-to-noise ratio, and contrast-to-noise ratio), subjective IQ, noise, and motion artifacts were analyzed overall and vessel-based with a 5-point Likert scale. Results: The CT attenuation of coronary arteries and image noise in group B were significantly higher than those in, group A (ranges: 507.5-548.1 Hounsfield units vs 407.5-444.5 Hounsfield units; and 20.3 +/- 8.6 vs 17.7 +/- 8.0) (P <= 0.0166), There was no significant difference between the two groups in signal-to-noise ratio, contrast-to-noise ratio, and subjective IQ of coronary arteries (29.4-31.7, 30.0-37.0, and medium score of 5 in group A vs 29.4-32.4, 27.7-36.3, and medium score of 5 in group B, respectively, P >= 0.1859). Both mean CTDI,, and dose length product in group B were 58% of those of group A. Conclusions: HCCM combined with low tube current allows dose reduction in coronary computed tomography angiography and does not compromise IQ. (C) 2017 The Association of University Radiologists. Published by Elsevier Inc. All rights reserved.
推荐引用方式
GB/T 7714：

Sun Yibo,Hua Yanqing,Wang Mingpeng, et al. Evaluation of a High Concentrated Contrast Media Injection Protocol in Combination with Low Tube Current for Dose Reduction in Coronary Computed Tomography Angiography: A Randomized, Two-center Prospective Study [J].ACADEMIC RADIOLOGY,2017,24(12):1482-1490.
APA：

Sun Yibo,Hua Yanqing,Wang Mingpeng,Mao Dingbiao,&Xu Jianrong.(2017).Evaluation of a High Concentrated Contrast Media Injection Protocol in Combination with Low Tube Current for Dose Reduction in Coronary Computed Tomography Angiography: A Randomized, Two-center Prospective Study .ACADEMIC RADIOLOGY,24(12):1482-1490.
MLA：

Sun Yibo, et al. "Evaluation of a High Concentrated Contrast Media Injection Protocol in Combination with Low Tube Current for Dose Reduction in Coronary Computed Tomography Angiography: A Randomized, Two-center Prospective Study" .ACADEMIC RADIOLOGY 24,12(2017):1482-1490.

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