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Multimodality Treatment of Pancreatic Cancer With Liver Metastases Using Chemotherapy, Radiation Therapy, and/or Chinese Herbal Medicine 期刊论文

编号：

5105f048-e4d6-4127-a5bb-f9deac9812e0
作者：

Ouyang, Huaqiang^[1,2];Wang, Peng^[1,2];Meng, Zhiqiang^[1,2];Chen, Zhen^[1,2];Yu, Er'xin^[1,2];Jin, Huan(金欢)^[3]Chang, David Z.^[4];Liao, Zhongxing^[5];Cohen, Lorenzo^[6,7,8];Liu, Luming^[1,2];
语种：

English
期刊：

PANCREAS ISSN：0885-3177 2011 年 40 卷 1 期 (120 - 125) ; JAN
收录：
关键词：

pancreatic cancer liver metastases multimodality treatment prognosis
摘要：

Objective: To explore the utility of multidisciplinary approaches in the treatment of patients with pancreatic cancer with liver metastases (PCLM). Methods: From 2002 to 2007, a total of 164 consecutive patients with PCLM treated with chemotherapy, radiation therapy, and/or Chinese herbal medicine were included in this study. Clinical parameters, treatments received, and survival time from initial diagnosis were analyzed. Results: Of the 164 patients, 113 (69%) were men and 51 (31%) were women, with median age of 58 years. One hundred thirty-two patients (80%) had synchronous liver metastases, and 57 patients (35%) had extrahepatic metastases. Overall median survival time of the 164 patients was 4.7 months; 23 (14%) were alive at least 12 months after initial diagnosis of liver metastases. Karnofsky performance status of less than 80, weight loss (>10% within 6 months), ascites, and carbohydrate antigen 19-9 of 1000 U/mL or greater were the most relevant predictors of poor survival. Multivariate analysis showed that chemotherapy and Chinese herbal medicine were protective factors. Conclusions: Multimodality treatment is well tolerated by patients with PCLM and may be effective in prolonging their survival. Awareness of the implications of these prognostic factors may assist in evaluating the survival potential of patients and selecting the most appropriate treatments.
推荐引用方式
GB/T 7714：

Ouyang Huaqiang,Wang Peng,Meng Zhiqiang, et al. Multimodality Treatment of Pancreatic Cancer With Liver Metastases Using Chemotherapy, Radiation Therapy, and/or Chinese Herbal Medicine [J].PANCREAS,2011,40(1):120-125.
APA：

Ouyang Huaqiang,Wang Peng,Meng Zhiqiang,Chen Zhen,&Liu Luming.(2011).Multimodality Treatment of Pancreatic Cancer With Liver Metastases Using Chemotherapy, Radiation Therapy, and/or Chinese Herbal Medicine .PANCREAS,40(1):120-125.
MLA：

Ouyang Huaqiang, et al. "Multimodality Treatment of Pancreatic Cancer With Liver Metastases Using Chemotherapy, Radiation Therapy, and/or Chinese Herbal Medicine" .PANCREAS 40,1(2011):120-125.

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