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ADC at 3.0 T as a noninvasive biomarker for preoperative prediction of Ki67 expression in invasive ductal carcinoma of breast 期刊论文

编号：

5193b12a-926e-4243-8240-d4872efa9f41
作者：

Shen, Lu^[1];Zhou, Guoxing^[1];Tong, Tong(童彤)^[2]Tang, Fei^[1];Lin, Yi^[1];Zhou, Jie^[1];Wang, Yibin^[1];Zong, Genlin^[1];Zhang, Lei^[1];
语种：

English
期刊：

CLINICAL IMAGING ISSN：0899-7071 2018 年 52 卷 (16 - 22) ; NOV-DEC
收录：
关键词：

Invasive ductal carcinoma Diffusion weighted imaging Ki67 Magnetic resonance imaging
摘要：

Purpose: To investigate the role of apparent diffusion coefficient (ADC) as an imaging biomarker for invasive ductal carcinoma (IDC) in the breast. Methods: Seventy-one patients undergoing 3.0 Tesla DWI were retrospectively enrolled. Correlations between the ADC values and prognostic factors were evaluated. Results: Multivariate regression analyses showed that Ki67 expression and molecular subtype were independently associated with the ADC. Discriminant analysis excluded the ADC as a good biomarker for subtype, but the mean ADC significantly distinguished Ki67-positive (low ADC) from Ki67-negative (high ADC) lesions, as observed in the in ROC curves, with a diagnostic sensitivity of 1.00 and a cut-off value of 0.97 x 10(-3)mm(2) /s. Conclusion: The ADC may be helpful for predicting Ki67 expression in IDC preoperatively.
推荐引用方式
GB/T 7714：

Shen Lu,Zhou Guoxing,Tong Tong, et al. ADC at 3.0 T as a noninvasive biomarker for preoperative prediction of Ki67 expression in invasive ductal carcinoma of breast [J].CLINICAL IMAGING,2018,52:16-22.
APA：

Shen Lu,Zhou Guoxing,Tong Tong,Tang Fei,&Zhang Lei.(2018).ADC at 3.0 T as a noninvasive biomarker for preoperative prediction of Ki67 expression in invasive ductal carcinoma of breast .CLINICAL IMAGING,52:16-22.
MLA：

Shen Lu, et al. "ADC at 3.0 T as a noninvasive biomarker for preoperative prediction of Ki67 expression in invasive ductal carcinoma of breast" .CLINICAL IMAGING 52(2018):16-22.

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