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TTRAP is a novel PML nuclear bodies-associated protein  期刊论文  

  • 编号:
    56c09102-0da4-4a39-b6cf-c563744ea0e5
  • 作者:
    Xu, Guanlan[1] Pan, Yukun[1] Wang, Bingyin[1] Huang, Lu[1] Tian, Ling[1] Xue, Jinglun[1] Chen, Jinzhong[1] Jia, William[1,2]
  • 语种:
    English
  • 期刊:
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS ISSN:0006-291X 2008 年 375 卷 3 期 (395 - 398) ; OCT 24
  • 收录:
  • 关键词:
  • 摘要:

    PML nuclear body (PML NB) is an important macromolecular nuclear structure that is involved in many essential aspects of cellular function. Tens of proteins have been found in PML NBs, and promyelocytic leukemia protein (PML) has been proven to be essential for the formation of this structure. Here, we showed that TRAF and TNF receptor-associated protein (TTRAP) was a novel PML NBs-associated protein. TTRAP colocalized with three important PML NBs-associated proteins, PML, DAXX and Sp100 in the typical fashion of PML NBs. By yeast mating assay, TTRAP was identified to interact with these PML NBs-associated proteins. The transcription and expression of TTRAP could be induced by IFN-gamma, representing another common feature of PML NBs-associated proteins. These results would not only be important for understanding PML NBs but also be helpful in Studying the TTRAP function in the future. (C) 2008 Elsevier Inc. All rights reserved.

  • 推荐引用方式
    GB/T 7714:
    Xu Guan-lan,Pan Yu-kun,Wang Bing-yin, et al. TTRAP is a novel PML nuclear bodies-associated protein [J].BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2008,375(3):395-398.
  • APA:
    Xu Guan-lan,Pan Yu-kun,Wang Bing-yin,Huang Lu,&Jia William.(2008).TTRAP is a novel PML nuclear bodies-associated protein .BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,375(3):395-398.
  • MLA:
    Xu Guan-lan, et al. "TTRAP is a novel PML nuclear bodies-associated protein" .BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 375,3(2008):395-398.
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