[1]Fudan University, Department of Chemistry and Laser Chemistry Institute,Shanghai,China
[2]Fudan University, Department of Electronics Engineering,Shanghai,China
[3]Fudan University, Department of Chemistry,Shanghai,China
[4]University of California, San Diego, Section of Cell and Developmental Biology,San Diego,United States
[5]National Institute of Metrology China,Beijing,China
[6]China Pharmaceutical University, Department of Pharmaceutical Analysis,Nanjing,China
[7]Fudan University, School of Chemistry,Shanghai,China
Collision-induced dissociation (CID) in linear ion traps is usually performed by applying a dipolar alternating current (AC) signal to one pair of electrodes, which results in ion excitation mainly in one direction. In this paper, we report simulation and experimental studies of the ion excitation in two coordinate directions by applying identical dipolar AC signals to two pairs of electrodes simultaneously. Theoretical analysis and simulation results demonstrate that the ion kinetic energy is higher than that using the conventional CID method. Experimental results show that more activation energy (as determined by the intensity ratio of the a