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Impact of premature ovarian failure on mortality and morbidity among Chinese women  期刊论文  

  • 编号:
    5c8d932d-58f9-40ae-b8bb-7194a0befe4d
  • 作者:
    Wu, Xiaoyan[0][1] Cai, Hui[1][2] Kallianpur, Asha R.[2][3] Li, Honglan[3][4] Yang, Gong[4][2] Gao, Jing[5][5] Xiang, Yongbing[6][6] Ji, Butian[7][7] YuTang, [8][8] Zheng, Wei[9][2] Shu, Xiaoou[10][2]
  • 地址:

    [1]Harbin Medical University, Department of Biostatistics,Harbin,China

    [2]Vanderbilt Ingram Cancer Center, Department of Medicine,Nashville,United States

    [3]Cleveland Clinic Foundation, Genomic Medicine Institute,Cleveland,United States

    [4]Renji Hospital, Shanghai Cancer Institute,Shanghai,China

    [5]Renji Hospital, SKLORG & Department of Epidemiology,Shanghai,China

    [6]Renji Hospital, Department of Epidemiology,Shanghai,China

    [7]National Cancer Institute, Department of Health and Human Services,Bethesda,United States

    [8]Medical Center of Fudan University, Department of Epidemiology,Shanghai,China

  • Scopus被引频次:
    12 次
  • 语种:
    英文
  • 期刊:
    PLoS ONE ISSN:1932-6203 2014 年 9 卷 3 期
  • 收录:
  • 摘要:

    Objective: To evaluate associations of premature ovarian failure (POF) with mortality and morbidity in Asian populations. Methods: We identified 1,003 cases of POF among 36,402 postmenopausal women who participated in the Shanghai Women's Health Study, a population-based cohort study. Cox regression and logistic regression models were applied in data analysis. Results: After adjustment for potential confounding factors, we found that POF increased the risk of total and cancer-specific mortality (HR (95%CIs): 1.29 (1.08-1.54) and 1.38 (1.05-1.81), respectively). POF was also associated with high prevalence of autoimmune disease (OR (95%CI): 1.56 (1.04-2.35)) but decreased incidence of breast cancer (OR (95%CI): 0.59 (0.38-0.91)). Similar results were observed when hormone replacement therapy users were excluded from the analysis. POF is associated with high waist-to-hip ratio. Conclusions: Our results suggest that women with POF experience increased mortality and that these women may benefit from heightened surveillance and appropriate interventions. © 2014 Wu et al.

  • 推荐引用方式
    GB/T 7714:
    Wu Xiaoyan/55715093400[0],Cai Hui/12802855000[1],Kallianpur Asha R./6602198349[2], et al. Impact of premature ovarian failure on mortality and morbidity among Chinese women [J].PLoS ONE,2014,9(3).
  • APA:
    Wu Xiaoyan/55715093400[0],Cai Hui/12802855000[1],Kallianpur Asha R./6602198349[2],Li Honglan/8908140600[3],&Shu Xiaoou/55630916600[10].(2014).Impact of premature ovarian failure on mortality and morbidity among Chinese women .PLoS ONE,9(3).
  • MLA:
    Wu Xiaoyan/55715093400[0], et al. "Impact of premature ovarian failure on mortality and morbidity among Chinese women" .PLoS ONE 9,3(2014).
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