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Incorporation of NLR into NIH stratification system increases predictive accuracy for surgically resected gastrointestinal stromal tumors 期刊论文

编号：

60b713e5-ba6f-41ba-b61b-1482a79391ca
作者：

Xue, Anwei(薛安慰)^[1]Gao, Xiaodong^[1];Fang, Yong(方勇)^[1]Shu, Ping(束平)^[1]Ling, Jiaqian(凌佳倩)^[1]Shen, Kuntang^[1];Sun, Yihong(孙益红)^[1]Qin, Xinyu(秦新裕)^[1]Hou, Yingyong(侯英勇)^[2]
语种：

English
期刊：

ACTA BIOCHIMICA ET BIOPHYSICA SINICA ISSN：1672-9145 2017 年 49 卷 2 期 (179 - 185) ; FEB
收录：
关键词：

neutrophil-to lymphocyte ratio gastrointestinal stromal tumors prognosis
摘要：

Previous studies have reported that preoperative neutrophil-to-lymphocyte (NLR) and platelet-to-lymphocyte ratios were prognostic for various types of cancers. The aim of this study was to investigate the predictive utilities of preoperative peripheral blood counts in patients with gastrointestinal stromal tumors (GISTs). We enrolled 510 consecutive, previously untreated patients who underwent surgery for primary, localized GISTs. The relationship between recurrence-free survival and outcome variables was assessed by univariate and multivariate analyses, while the clinicopathologic relevance of NLR was determined using the Chi-square test. A preoperative NLR >= 2 was associated with poor prognosis in patients undergoing surgeries for primary, localized GISTs. It was an independent predictor only in patients classified as National Institutes of Health high risk but not in the entire population. Preoperative NLR is a feasible and reproducible peripheral biomarker that helps identify patients for intensive adjuvant therapy and frequent surveillance.
推荐引用方式
GB/T 7714：

Xue Anwei,Gao Xiaodong,Fang Yong, et al. Incorporation of NLR into NIH stratification system increases predictive accuracy for surgically resected gastrointestinal stromal tumors [J].ACTA BIOCHIMICA ET BIOPHYSICA SINICA,2017,49(2):179-185.
APA：

Xue Anwei,Gao Xiaodong,Fang Yong,Shu Ping,&Hou Yingyong.(2017).Incorporation of NLR into NIH stratification system increases predictive accuracy for surgically resected gastrointestinal stromal tumors .ACTA BIOCHIMICA ET BIOPHYSICA SINICA,49(2):179-185.
MLA：

Xue Anwei, et al. "Incorporation of NLR into NIH stratification system increases predictive accuracy for surgically resected gastrointestinal stromal tumors" .ACTA BIOCHIMICA ET BIOPHYSICA SINICA 49,2(2017):179-185.

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