[1]Fudan University, Department of Physics,Shanghai,China
[2]Fudan University, Department of Trauma-Emergency and Critical Care Medicine,Shanghai,China
[3]Zhongshan Hospital Shanghai, Department of Cardiology,Shanghai,China
[4]Fudan University, Department of Cardiology,Shanghai,China
[5]Fudan University, Department of Endocrinology,Shanghai,China
This study aimed to evaluate the effect of high level cardiac troponin I (cTnI) on one-year survival rate of non-cardiac critically ill patients. A total of 153 noncardiac critically ill patients were enrolled in our research. Serum cTnI and CK-MB (creatine kinase-MB) levels were measured simultaneously on admission. Clinical and laboratory parameters were recorded and compared between these two groups. In addition, we evaluated the one-year survival rate among patients with high cTnI level and normal cTnI level. CK-MB levels, LVEF (left ventricular ejection fraction) and the length of hospitalization didn't show any significant differences between the two groups (P > 0.05). APACHE (Acute Physiology and Chronic Health Enquiry) II scores, usage of mechanic ventilation and MODS (Multiple Organ Dysfunction Syndrome) incidence of high cTnI group were significantly increased compared with normal cTnI group (P < 0.05). The one-year survival rate of high cTnI group was lower than normal cTnI group (log-rank test, χ2 = 4.29, P < 0.05). Non-cardiac critically ill patients with high cTnI levels presented low one-year survival rate. cTnI level can be used as a maker to predict short time survival in non-cardiac critically ill patients.