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A new assay for CCR5del32 mutation: Genotyping through the number of fragments amplified 期刊论文

编号：

738772ac-2045-4c5f-a360-550ed8239489
作者：

Wang, QingLin[0]^[1] Xiao, Li[1]^[2] Zhang, Jia[2]^[1] He, Nongyue[3]^[3] Lu, Xueguan[4]^[4] Li, Ping[5]^[5] Li, Kai[6]^[6]
地址：

[1]Soochow University, Department of Molecular Diagnostics and Biopharmaceutics,Suzhou,China
[2]Wuhan University, Department of Engineering Mechanics,Wuhan,China
[3]Southeast University, State Key Laboratory of Bioelectronics,Nanjing,China
[4]Fudan University Shanghai Cancer Center, Department of Radiation Oncology,Shanghai,China
[5]China Academy of Engineering Physics, Laboratory for Shock Wave and Detonation Physics Research,Chengdu,China
[6]Soochow University, College of Pharmaceutical Sciences,Suzhou,China
语种：

英文
期刊：

Journal of Biomedical Nanotechnology ISSN：1550-7033 2011 年 7 卷 6 期 (754 - 758)
收录：
关键词：

CCR5del32 Deletion HIV-1 Number of fragments
摘要：

CCR5 is a coreceptor for the entry of HIV into CD4+ cells and some of its natural mutants possess potential protection against HIV-1 infection. Individuals with the CCR5-Δ32 genotype have a lower possibility of being infected with HIV and take longer to progress to AIDS if infected. The present study demonstrated a new primer extension assay for genetic analysis of the CCR5del32 mutation: each genotype is determined by a specific number of fragments amplified. Quick and efficient screening and testing of this specific genotype is clinically useful in epidemiological study, risk analysis, and determining donors for allogenic stem cell transplantation. Copyright ? 2011 American Scientific Publishers All rights reserved.
推荐引用方式
GB/T 7714：

Wang QingLin/55698291800[0],Xiao Li/36619895200[1],Zhang Jia/8872599200[2], et al. A new assay for CCR5del32 mutation: Genotyping through the number of fragments amplified [J].Journal of Biomedical Nanotechnology,2011,7(6):754-758.
APA：

Wang QingLin/55698291800[0],Xiao Li/36619895200[1],Zhang Jia/8872599200[2],He Nongyue/26643550300[3],&Li Kai/57001317600[6].(2011).A new assay for CCR5del32 mutation: Genotyping through the number of fragments amplified .Journal of Biomedical Nanotechnology,7(6):754-758.
MLA：

Wang QingLin/55698291800[0], et al. "A new assay for CCR5del32 mutation: Genotyping through the number of fragments amplified" .Journal of Biomedical Nanotechnology 7,6(2011):754-758.

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