[1]China Medical University Shenyang, Department of Obstetrics and Gynecology,Shenyang,China
[2]China Medical University Shenyang, Department of Clinical Epidemiology,Shenyang,China
[3]China Medical University Shenyang, Department of Pediatrics,Shenyang,China
[4]China Medical University Shenyang, Department of General Surgery,Shenyang,China
[5]China Medical University Shenyang, Department of Neurology,Shenyang,China
[6]Capital Medical University China, Beijing Obstetrics and Gynecology Hospital,Beijing,China
[7]Guangzhou Medical University, Department of Pediatric Surgery,Guangzhou,China
[8]Fudan University,Shanghai,China
[9]Tongji University, Department of Obstetrics,Shanghai,China
[10]Guangzhou Medical University, Third Hospital,Guangzhou,China
[11]Shandong University, Department of Obstetrics and Gynecology,Jinan,China
[12]Sun Yat-Sen University, Department of Obstetrics and Gynecology,Guangzhou,China
[13]Chongqing Medical University,Chongqing,China
[14]Peking University, Department of Obstetrics and Gynecology,Beijing,China
[15]Nanjing Medical University, First Clinical Medical College,Nanjing,China
Complications in women with multiple gestation pregnancy have not been studied in China. We aimed to establish a database of women with multiple gestation pregnancy and investigate the complications related to multiple pregnancy. We conducted a cross-sectional study that included 3246 women with multiple gestation pregnancy and who had multiple live-birth deliveries; the women were registered at ten maternal-fetal medicine centers in China in 2013. All participants completed a detailed questionnaire that included basic demographic information, history of gestation and abnormal fetal development, risk factors during pregnancy, and pregnancy outcomes. Overall, 1553 (47.8%) women experienced pregnancy complications; these women were more likely to have lower height and less education than women who did not experience complications. However, women who experienced complications had a higher twin birth rate and were more likely to have received regular antenatal care and assisted reproductive technology than women without complications (P < 0.05). Notably, preterm birth was a primary complication in multiple pregnancy (n = 960). In conclusion, pregnancy complications, especially preterm birth, were relatively common in women with multiple gestation pregnancy. The findings from this cross-sectional study in China may be used as a foundation for investigating risk factors for complications in women with multiple gestation pregnancy in the future.