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Instantaneous fluorescent probe for the specific detection of H2S 期刊论文

编号：

80e345f3-f85c-424a-a616-0653fc19e9f3
作者：

Lin, Xianfeng^[1];Lu, Xiuhong^[1];Zhou, Junliang(周军良)^[1]Ren, Hang^[1];Dong, Xiaochun(董肖椿)^[1]Zhao, Weili(赵伟利)*^[1,2]Chen, Zhongjian^[3];
语种：

英文
期刊：

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY ISSN：1386-1425 2019 年 213 卷 (416 - 422) ; APR 15
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关键词：

Fluorescent probe H2S Lysosome-targeted
摘要：

Novel cyanine-based fluorescent probes for the detection of H2S were developed. The probes developed are stable under physiological conditions. The water soluble fluorescent probe 2 displayed ultrafast and specific response to H2S displaying NIR fluorescence of 115-fold turn-on with the detection limit of 11 nM without assistance of organic solvent or surfactant. Cell imaging experiments indicated that probe 2 was cellpermeable and was able to detect H2S sensitively in lysosomes. Moreover, our probe was able to detect H2S intrinsically produced H2S through enzymatic/non-enzymatic biosynthetic pathway from Cys/GSH. Moreover, we applied probe 2 to detect H2S in living mice and demonstrated the fast metabolism of H2S. Thus, probe 2 shows great promise as a reporter for H2S. (C) 2019 Elsevier B.V. All rights reserved.
推荐引用方式
GB/T 7714：

Lin Xianfeng,Lu Xiuhong,Zhou Junliang, et al. Instantaneous fluorescent probe for the specific detection of H2S [J].SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,2019,213:416-422.
APA：

Lin Xianfeng,Lu Xiuhong,Zhou Junliang,Ren Hang,&Chen Zhongjian.(2019).Instantaneous fluorescent probe for the specific detection of H2S .SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,213:416-422.
MLA：

Lin Xianfeng, et al. "Instantaneous fluorescent probe for the specific detection of H2S" .SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY 213(2019):416-422.
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