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Value of three-dimensional speckle tracking echocardiography to assess left ventricular function in hyperuricemia patients 期刊论文

编号：

9489637a-d7bb-49b2-aa46-e8201fa5e63f
作者：

Zhang, Xiaojie(张晓洁)#^[1]Lu, Qing^[2];Zhang, Zhuojun(张卓君)^[1]Chen, Yongle^[3];Wang, Yanan^[3];Wang, Youngshi^[3];Li, Zheng^[3];Jiang, Lindi(姜林娣)*^[1,4]
语种：

English
期刊：

CLINICAL RHEUMATOLOGY ISSN：0770-3198 2018 年 37 卷 9 期 (2539 - 2545) ; SEP
收录：
关键词：

Global circumferential strain Hyperuricemia Left ventricular function Three-dimensional speckle tracking echocardiography
摘要：

To assess the value of three-dimensional speckle tracking echocardiography (3D STE) in evaluating the left ventricular (LV) function in hyperuricemia patients. We enrolled 15 healthy controls and 40 hyperuricemia patients and collected and analyzed full-volume 3D STE images of the left ventricle in the apical four-chamber heart view. Laboratory tests and 3D STE parameters, including left ventricular ejection fraction, left ventricular end-diastolic volume, left ventricular end-systolic volume, stroke volume (SV), global longitudinal strain (GLS), and global circumferential strain (GCS), were compared between hyperuricemia patients and healthy controls. Hypenuicemia patients exhibited higher body mass index (24.70 +/- 2.9 vs. 21.83 +/- 2.4 kg/m(2), p = 0.001), C-reactive protein (5.82 +/- 9.4 vs. 1.12 +/- 1.8 g/L, p = 0.012), alanine transaminase (34.26 +/- 26.6 vs. 17.60 +/- 13.0 U/L, p = 0.011), aspartate transaminase (24.90 +/- 11.3 vs. 17.70 +/- 4.1 U/L, p = 0.001), blood urea nitrogen (5.11 +/- 1.6 vs. 4.18 +/- 0.6 mmol/ L, p= 0.046), and serum creatinine (90.25 +/- 14.6 vs. 77.93 +/- 10.8 mu mol/L, p= 0.006) levels, as well as a lower estimated glomerular filtration rate (87.87 +/- 16.5 vs. 103.64 +/- 11.3 mL/min/1.73m(2), p= 0.002). The 3D STE parameters reflecting LV function, including SV (54.71 +/- 9.6 vs. 61.92 +/- 14.4 mL, p= 0.024), GLS (- 20.51 +/- 4.0 vs. - 23.20 +/- 4.0%, p = 0.019), and GCS (- 31.30 +/- 5.0 vs. - 35.65 +/- 2.5%, p = 0.000), were significantly decreased in hyperuricemia patients. Furthermore, GCS was significantly correlated with the serum uric acid (sUA) level even after adjustment of confounding variables like age, body mass index, and serum creatinine. 3D STE is a novel technique for recognizing the early decline in LV function, with GLS and GCS serving as reliable indicators, in hyperuricemia patients. Moreover, the degree of decline in LV function may be conflated with the sUA level in hyperuricemia patients.
推荐引用方式
GB/T 7714：

Zhang Xiaojie,Lu Qing,Zhang Zhuojun, et al. Value of three-dimensional speckle tracking echocardiography to assess left ventricular function in hyperuricemia patients [J].CLINICAL RHEUMATOLOGY,2018,37(9):2539-2545.
APA：

Zhang Xiaojie,Lu Qing,Zhang Zhuojun,Chen Yongle,&Jiang Lindi.(2018).Value of three-dimensional speckle tracking echocardiography to assess left ventricular function in hyperuricemia patients .CLINICAL RHEUMATOLOGY,37(9):2539-2545.
MLA：

Zhang Xiaojie, et al. "Value of three-dimensional speckle tracking echocardiography to assess left ventricular function in hyperuricemia patients" .CLINICAL RHEUMATOLOGY 37,9(2018):2539-2545.

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