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Evaluation of acute kidney injury as defined by the risk, injury, failure, loss, and end-stage criteria in critically ill patients undergoing abdominal aortic aneurysm repair 期刊论文

编号：

950d8ace-2870-480b-8dcb-930c0e3e4079
作者：

Yue Jianing(岳嘉宁)^[1]Luo Zhe^[2,3];Guo Daqiao(郭大乔)^[1]Xu Xin(徐欣)^[1]Chen Bin(陈斌)^[1]Jiang Junhao(蒋俊豪)^[1]Yang Jue(杨珏)^[1]Shi Zhenyu(史振宇)^[1]Zhu Ting^[1];Ju Minjie^[2,3];Tu Guowei^[2,3];Wang Yuqi(王玉琦)^[1]Zhu Duming^[2,3];Fu Weiguo(符伟国)^[1]
语种：

English
期刊：

CHINESE MEDICAL JOURNAL ISSN：0366-6999 2013 年 126 卷 3 期 (431 - 436) ; FEB 5
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关键词：

abdominal aortic aneurysm acute kidney injury risk, injury, failure, loss, and end-stage critical care goal-directed endovascular
摘要：

Background Acute kidney injury (AKI) is considered as a common and significant complication following abdominal aortic aneurysm (AAA) repair. This study aimed to assess the associated risk factors of AKI in the critically ill patients undergoing AAA repair and to evaluate the appropriate AKI management in the specific population. Methods We retrospectively examined data from all critically ill patients undergoing AAA repairs at our institution from April 2007 to March 2012. Multivariable analysis was used to identify factors associated with postoperative AKI, which was defined by risk, injury, failure, loss and end-stage (RIFLE) kidney disease criteria. The goal-directed hemodynamic optimization (maintenance of optimal hemodynamics and neutral or negative fluid balance) and renal outcomes were also reviewed. Results Of the 71 patients enrolled, 32 (45.1%) developed AKI, with 30 (93.8%) cases diagnosed on admission to surgical intensive care unit (SICU). Risk factors for AKI were ruptured AAA (odds ratio (OR)=5.846, 95% confidence interval (CI): 1.346-25.390), intraoperative hypotension (OR=6.008, 95% CI: 1.176 to 30.683), and perioperative blood transfusion (OR=4.611, 95% CI: 1.307-16.276). Goal-directed hemodynamic optimization resulted in 75.0% complete and 18.8% partial renal recovery. Overall in-hospital mortality was 2.8%. AKI was associated with significantly increased length of stay ((136.9 +/- 24.5) hours vs. (70.4 +/- 11.3) hours) in Surgical Intensive Care Unit. Conclusions Critically ill patients undergoing AAA repair have a high incidence of AKI, which can be early recognized by RIFLE criteria. Rupture, hypotension, and blood transfusion are the significant associated risk factors. Application of goal-directed hemodynamic optimization in this cohort appeared to be effective in improving renal outcome.
推荐引用方式
GB/T 7714：

Yue Jia-ning,Luo Zhe,Guo Da-qiao, et al. Evaluation of acute kidney injury as defined by the risk, injury, failure, loss, and end-stage criteria in critically ill patients undergoing abdominal aortic aneurysm repair [J].CHINESE MEDICAL JOURNAL,2013,126(3):431-436.
APA：

Yue Jia-ning,Luo Zhe,Guo Da-qiao,Xu Xin,&Fu Wei-guo.(2013).Evaluation of acute kidney injury as defined by the risk, injury, failure, loss, and end-stage criteria in critically ill patients undergoing abdominal aortic aneurysm repair .CHINESE MEDICAL JOURNAL,126(3):431-436.
MLA：

Yue Jia-ning, et al. "Evaluation of acute kidney injury as defined by the risk, injury, failure, loss, and end-stage criteria in critically ill patients undergoing abdominal aortic aneurysm repair" .CHINESE MEDICAL JOURNAL 126,3(2013):431-436.

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