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High prevalence and correlates of human herpesvirus-6A in nevocytic nevus and seborrheic diseases: Implication from a pilot study of skin patient tissues in Shanghai 期刊论文

编号：

9e621a4f-f5d4-4dde-8d74-0e33eb6e0c6d
作者：

Ding, Ling^[1,2];Mo, Xiaohui^[1,2,4];Zhang, Liming^[6];Zhou, Feng(周峰)^[1,2,7]Zhu, Caixia(朱彩霞)^[1,2]Wang, Yuyan^[1,2];Cai, Cankun^[1,2];Liu, Yeqiang^[5];Wei, Fang^[3];Cai, Qiliang(蔡启良)^[1,2]
语种：

English
期刊：

JOURNAL OF MEDICAL VIROLOGY ISSN：0146-6615 2018 年 90 卷 9 期 (1532 - 1540) ; SEP
收录：
关键词：

epidemiology Epstein-Barr virus (EBV) herpesvirus human herpesvirus (HHV) 6 Human herpesvirus 8 (Kaposi sarcoma-associated herpesvirus)
摘要：

Skin disorders vary greatly in symptom and severity, and the causes of these disorders are largely unknown. Human herpesvirus (HHV) has been shown to cause many diseases. However, the prevalence and correlation of each HHV infection with different skin disorders remains obscure. To reveal the potential link of a certain type of skin disease with herpesvirus infection, a total of 272 patient tissues with inflammatory or neoplastic skin diseases including 7 subtypes in Shanghai, China, were investigated. We found that the overall prevalence of HHV-6A in inflammatory or neoplastic skin tissues is the most common (40.3%), followed by Epstein-Barr virus (17.6%), Kaposi's sarcoma-associated herpesvirus (KSHV; 9.2%), HHV-6B (4.4%), human cytomegalovirus (1.1%), and varicella-zoster virus (0.7%); albeit the co-infection of HHV-6A, Epstein-Barr virus, and KSHV presents to a less extent and none of HSV-1, HSV-2, or HHV-7 were detected. Moreover, HHV-6A infection is highly associated with nevocytic nevus and seborrheic dermatitis/keratosis diseases, which mainly occur in the head and the neck or the lower limb. Despite no significant difference among the HHV infections in different age groups of skin patient tissues, the distribution of KSHV infection was exclusively and significantly higher (3.7-fold) inmale skin patients.
推荐引用方式
GB/T 7714：

Ding Ling,Mo Xiaohui,Zhang Liming, et al. High prevalence and correlates of human herpesvirus-6A in nevocytic nevus and seborrheic diseases: Implication from a pilot study of skin patient tissues in Shanghai [J].JOURNAL OF MEDICAL VIROLOGY,2018,90(9):1532-1540.
APA：

Ding Ling,Mo Xiaohui,Zhang Liming,Zhou Feng,&Cai Qiliang.(2018).High prevalence and correlates of human herpesvirus-6A in nevocytic nevus and seborrheic diseases: Implication from a pilot study of skin patient tissues in Shanghai .JOURNAL OF MEDICAL VIROLOGY,90(9):1532-1540.
MLA：

Ding Ling, et al. "High prevalence and correlates of human herpesvirus-6A in nevocytic nevus and seborrheic diseases: Implication from a pilot study of skin patient tissues in Shanghai" .JOURNAL OF MEDICAL VIROLOGY 90,9(2018):1532-1540.

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