Meiosis halves diploid chromosome numbers to haploid levels that are essential for sexual reproduction in most eukaryotes. Meiotic recombination ensures the formation of bivalents between homologous chromosomes (homologs) and their subsequent proper segregation. It also results in genetic diversity among progeny that influences evolutionary responses to selection. Moreover, crop breeding depends upon the action of meiotic recombination to rearrange elite traits between parental chromosomes. An understanding of the molecular mechanisms that drive meiotic recombination is important for both fundamental research and practical applications. This review emphasizes advances made during the past 5 years, primarily in Arabidopsis and rice, by summarizing newly characterized genes and proteins and examining the regulatory mechanisms that modulate their action.
[1]Fudan Univ, State Key Lab Genet Engn, Shanghai 200438, Peoples R China.
[2]Fudan Univ, Collaborat Innovat Ctr Genet & Dev, Key Lab Biodivers Sci & Ecol Engn, Inst Plant Biol,Sch Life Sci,Minist Educ, Shanghai 200438, Peoples R China.
[3]Univ North Carolina Chapel Hill, Dept Biol, Chapel Hill, NC 27599 USA.
[4]Univ North Carolina Chapel Hill, Integrat Program Biol & Genome Sci, Chapel Hill, NC 27599 USA.
[5]Univ N Carolina, Sch Med, Lineberger Comprehens Canc Ctr, Chapel Hill, NC 27599 USA.
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