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Animal models for bladder cancer: The model establishment and evaluation 期刊论文

编号：

a8343ba0-f01e-4f3c-9516-7edec7b83512
作者：

Zhang, Ning^[1,2];Li, Dongyang^[1,2];Shao, Jialiang(邵佳亮)^[1,2]Wang, Xiang(王翔)*^[1,2]
语种：

English
期刊：

ONCOLOGY LETTERS ISSN：1792-1074 2015 年 9 卷 4 期 (1515 - 1519) ; APR
收录：
关键词：

bladder cancer animal models orthotopic models heterotopic models living tissue grafting
摘要：

Bladder cancer is the most common type of tumor in the urogenital system. Approximately 75% of patients with bladder cancer present with non-muscle-invasive cancer, which is generally treated by transurethral resection and intravesical chemotherapy. In spite of different therapeutic options, there remains a very variable risk of recurrence and progression. Novel therapeutic methods of treating bladder cancer are urgently required. The exploration and preclinical evaluation of new treatments requires an animal tumor model that mimics the human counterpart. Animal models are key in bladder cancer research and provide a bridge to the clinic. Various animal bladder cancer models have been described to date, but the tumor take rate is reported to be 30-100%. Establishment of reliable, simple, practicable and reproducible animal models remains an ongoing challenge. The present review summarizes the latest developments with regard to the establishment of animal models and tumor evaluation.
推荐引用方式
GB/T 7714：

Zhang Ning,Li Dongyang,Shao Jialiang, et al. Animal models for bladder cancer: The model establishment and evaluation [J].ONCOLOGY LETTERS,2015,9(4):1515-1519.
APA：

Zhang Ning,Li Dongyang,Shao Jialiang,Wang Xiang.(2015).Animal models for bladder cancer: The model establishment and evaluation .ONCOLOGY LETTERS,9(4):1515-1519.
MLA：

Zhang Ning, et al. "Animal models for bladder cancer: The model establishment and evaluation" .ONCOLOGY LETTERS 9,4(2015):1515-1519.

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