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Folate-mediated chemotherapy and diagnostics: An updated review and outlook 期刊论文

编号：

aba9d522-dd32-4221-8d3f-f9571a4adbf0
作者：

Xu, Leyuan^[1,2] Bai, Qianming^[3,4] Zhang, Xin^[5] Yang, Hu^[1,6,7]
语种：

English
期刊：

JOURNAL OF CONTROLLED RELEASE ISSN：0168-3659 2017 年 252 卷 (73 - 82) ; APR 28
收录：
关键词：

Folic acid Folate receptor Targeted delivery Nanomedicine Diagnosis
摘要：

Folate receptor (FR) is highly expressed in many types of human cancers, and it has been actively studied for developing targeted chemotherapy and diagnostic agents. Tremendous efforts have been made in developing FR-targeted nanomedicines and nanoprobes and translating them into clinical applications. This article provides a concise review on the latest development of folate-mediated nanomedicines and nanoprobes for chemotherapy and diagnostics with an emphasis on in vivo applications. The cellular uptake mechanisms, pharmacokinetics (PK), administration routes and major challenges in FR-targeted nanoparticles are discussed. (C) 2017 Elsevier B.V. All rights reserved.
推荐引用方式
GB/T 7714：

Xu Leyuan,Bai Qianming,Zhang Xin, et al. Folate-mediated chemotherapy and diagnostics: An updated review and outlook [J].JOURNAL OF CONTROLLED RELEASE,2017,252:73-82.
APA：

Xu Leyuan,Bai Qianming,Zhang Xin,Yang Hu.(2017).Folate-mediated chemotherapy and diagnostics: An updated review and outlook .JOURNAL OF CONTROLLED RELEASE,252:73-82.
MLA：

Xu Leyuan, et al. "Folate-mediated chemotherapy and diagnostics: An updated review and outlook" .JOURNAL OF CONTROLLED RELEASE 252(2017):73-82.

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