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Cyclic helix B peptide ameliorates acute myocardial infarction in mice by inhibiting apoptosis and inflammatory responses 期刊论文

编号：

adb0beb6-21a8-4af1-8ce5-273e5fa44b98
作者：

Yang, Cheng(杨橙)#^[1,2,3]Zhang, Chao(张潮)#^[1,2]Jia, Jianguo(贾剑国)^[4,5]Wang, Lingyan^[6];Zhang, Weitao(张伟韬)^[1,2]Li, Jiawei^[1,2];Xu, Ming(许明)^[1,2]Rong, Ruiming(戎瑞明)*^[1,2,7]Zhu, Tongyu(朱同玉)*^[1,2]
语种：

英文
期刊：

CELL DEATH DISCOVERY ISSN：2058-7716 2019 年 5 卷 ; MAR 18
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摘要：

Cyclic helix B peptide (CHBP) is a peptide derivant of erythropoietin with powerful tissue-protective efficacies in a variety of organ injuries, but without erythropoietic effect. However, the role of CHBP in acute myocardial infarction (AMI) and related mechanisms are not studied yet. In this study, we found in a murine AMI model that the administration of CHBP could ameliorate cardiac injury, increase the survival rate, inhibit cardiomyocyte apoptosis, improve cardiac function and remodeling, and reduce the expression of inflammatory cytokines in the serum and kidney tissue both at 24 h and 8 weeks following AMI. This study suggests that CHBP has the potential to be used as an effective drug in the treatment of AMI.
推荐引用方式
GB/T 7714：

Yang Cheng,Zhang Chao,Jia Jianguo, et al. Cyclic helix B peptide ameliorates acute myocardial infarction in mice by inhibiting apoptosis and inflammatory responses [J].CELL DEATH DISCOVERY,2019,5.
APA：

Yang Cheng,Zhang Chao,Jia Jianguo,Wang Lingyan,&Zhu Tongyu.(2019).Cyclic helix B peptide ameliorates acute myocardial infarction in mice by inhibiting apoptosis and inflammatory responses .CELL DEATH DISCOVERY,5.
MLA：

Yang Cheng, et al. "Cyclic helix B peptide ameliorates acute myocardial infarction in mice by inhibiting apoptosis and inflammatory responses" .CELL DEATH DISCOVERY 5(2019).
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