首页 / 院系成果 / 成果详情页

Flexible approach for the asymmetric synthesis of (-)-hyacinthacine A1 and its 7a-epimer 期刊论文

编号：

ae3b77ad-2027-47f2-bc6c-ca52205ce2f3
作者：

Si, Changmei[0]^[1] Mao, Zhuoya[1]^[1] Ren, Rongguo[2]^[2] Du, Zhenting[3]^[3] Wei, Bangguo[4]^[1]
地址：

[1]Fudan University Shanghai Medical College, School of Life Sciences and Institutes of Biomedical Sciences,Shanghai,China
[2]Fudan University, Department of Chemistry,Shanghai,China
[3]Northwest A&F University, College of Sciences,Yangling,China
语种：

英文
期刊：

Tetrahedron ISSN：0040-4020 2014 年 70 卷 43 期 (7936 - 7941)
收录：
关键词：

Alkaloid Asymmetric synthesis Hyacinthacine Lactam Nucleophilic addition
摘要：

The diastereoselective nucleophilic addition of organic boronic ester to 3-hydroxy-2-substituted N-acyliminium ions 9 led to the formation of 2,5-cis-pyrrolidine 10, from which a convenient synthesis of (-)-7a-epi-1 was developed. In addition, an efficient asymmetric synthesis of (-)-hyacinthacine A1 1 was achieved through the reduction/ring-opening process. © 2014 Elsevier Ltd. All rights reserved.
推荐引用方式
GB/T 7714：

Si Changmei/54421166800[0],Mao Zhuoya/56372258000[1],Ren Rongguo/55255922700[2], et al. Flexible approach for the asymmetric synthesis of (-)-hyacinthacine A1 and its 7a-epimer [J].Tetrahedron,2014,70(43):7936-7941.
APA：

Si Changmei/54421166800[0],Mao Zhuoya/56372258000[1],Ren Rongguo/55255922700[2],Du Zhenting/7402288649[3],&Wei Bangguo/7202263536[4].(2014).Flexible approach for the asymmetric synthesis of (-)-hyacinthacine A1 and its 7a-epimer .Tetrahedron,70(43):7936-7941.
MLA：

Si Changmei/54421166800[0], et al. "Flexible approach for the asymmetric synthesis of (-)-hyacinthacine A1 and its 7a-epimer" .Tetrahedron 70,43(2014):7936-7941.

浏览次数：3  下载次数：0

分享到：

浏览次数：3

下载次数：0

打印次数：0