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Chemical constituents from Gueldenstaedtia verna and their anti-inflammatory activity 期刊论文

编号：

b7543971-9e6c-4025-96d7-09a1b5b60123
作者：

Liu, Xin^[1];Yin, Chengle(尹成乐)^[1]Cao, Yue^[1];Zhou, Jinge^[2];Wu, Tao^[2];Cheng, Zhihong(程志红)*^[1]
语种：

English
期刊：

NATURAL PRODUCT RESEARCH ISSN：1478-6419 2018 年 32 卷 10 期 (1145 - 1149)
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关键词：

Gueldenstaedtia verna triterpenoid glycoside anti-inflammatory inhibition of NO production
摘要：

A new triterpenoid glycoside (1) and 15 known compounds (2-16) were isolated from the whole plants of Gueldenstaedtia verna. The new compound (1) was identified as complogenin 22-O--d-glucopyranoside by extensive spectroscopic techniques including 1D (H-1 and C-13) and 2D NMR experiments (HSQC, HMBC and NOESY), HR-DART-MS and chemical methods. Most of the isolates were evaluated for their inhibitory activities on LPS-induced NO production in RAW 264.7 cells. The inhibitory effects of the active compounds, sulphuretin (8) and (22E,24S)-5,8-epidioxy-24-methyl-cholesta-6,9(11),22-trien-3-ol (13), on the production of pro-inflammatory mediators (including IL-6, IL1 and PGE(2)) were further estimated in vitro by ELISA in RAW 264.7 macrophages. [GRAPHICS] .
推荐引用方式
GB/T 7714：

Liu Xin,Yin Chengle,Cao Yue, et al. Chemical constituents from Gueldenstaedtia verna and their anti-inflammatory activity [J].NATURAL PRODUCT RESEARCH,2018,32(10):1145-1149.
APA：

Liu Xin,Yin Chengle,Cao Yue,Zhou Jinge,&Cheng Zhihong.(2018).Chemical constituents from Gueldenstaedtia verna and their anti-inflammatory activity .NATURAL PRODUCT RESEARCH,32(10):1145-1149.
MLA：

Liu Xin, et al. "Chemical constituents from Gueldenstaedtia verna and their anti-inflammatory activity" .NATURAL PRODUCT RESEARCH 32,10(2018):1145-1149.

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