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Electroacupuncture diminishes P2X(2) and P2X(3) purinergic receptor expression in dorsal root ganglia of rats with visceral hypersensitivity 期刊论文

编号：

b8384075-4847-493a-aea0-3a67e7e9b22a
作者：

Weng, Zhijun^[1] Wu, Luyi^[1] Lu, Yuan^[1] Wang, Lidong^[1] Tan, Linying^[1] Dong, Ming^[1] Xin, Yuhu^[2]
语种：

English
期刊：

NEURAL REGENERATION RESEARCH ISSN：1673-5374 2013 年 8 卷 9 期 (802 - 808) ; MAR
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关键词：

neural regeneration acupuncture and moxibustion P2X(2) P2X(3) visceral hypersensitivity irritable bowel syndrome electroacupuncture P2 purinergic receptors abdominal withdrawal reflex scores peripheral nerve injury grants-supported paper photographs-containing paper neuroregeneration
摘要：

Electroacupuncture at Shangjuxu (ST37) and Tianshu (ST25) can improve visceral hypersensitivity in rats. Colorectal distension was used to establish a rat model of chronic visceral hypersensitivity. Immunohistochemistry was used to detect P2X(2) and P2X(3) receptor expression in dorsal root ganglia from rats with chronic visceral hypersensitivity. Results demonstrated that abdominal withdrawal reflex scores obviously increased following establishment of the model, indicating visceral hypersensitivity. Simultaneously, P2X(2) and P2X(3) receptor expression increased in dorsal root ganglia. After bilateral electroadupuncture at Shangjuxu and Tianshu, abdominal withdrawal reflex scores and P2X(2) and P2X(3) receptor expression decreased in rats with visceral hypersensitivity. These results indicated that electroacupuncture treatment improved visceral hypersensitivity in rats with irritable bowel syndrome by reducing P2X(2) and P2X(3) receptor expression in dorsal root ganglia.
推荐引用方式
GB/T 7714：

Weng Zhijun,Wu Luyi,Lu Yuan, et al. Electroacupuncture diminishes P2X(2) and P2X(3) purinergic receptor expression in dorsal root ganglia of rats with visceral hypersensitivity [J].NEURAL REGENERATION RESEARCH,2013,8(9):802-808.
APA：

Weng Zhijun,Wu Luyi,Lu Yuan,Wang Lidong,&Xin Yuhu.(2013).Electroacupuncture diminishes P2X(2) and P2X(3) purinergic receptor expression in dorsal root ganglia of rats with visceral hypersensitivity .NEURAL REGENERATION RESEARCH,8(9):802-808.
MLA：

Weng Zhijun, et al. "Electroacupuncture diminishes P2X(2) and P2X(3) purinergic receptor expression in dorsal root ganglia of rats with visceral hypersensitivity" .NEURAL REGENERATION RESEARCH 8,9(2013):802-808.

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