首页 / 院系成果 / 成果详情页

Chiral Ferrocenyl N,N Ligands with Intramolecular Hydrogen Bonds for Highly Enantioselective Allylic Alkylations 期刊论文

编号：

bb28ff64-8b92-468b-95a2-5174bbe5514c
作者：

Yao, Lin^[1] Nie, Huifang^[1] Zhang, Dongxu^[1] Wang, Libin^[1] Zhang, Yuhao^[1] Chen, Weiping^[1] Li, Zhenhua^[2] Liu, Xueying^[1] Zhang, Shengyong^[1]
语种：

English
期刊：

CHEMCATCHEM ISSN：1867-3880 2018 年 10 卷 4 期 (804 - 809) ; FEB 21
收录：
关键词：

alkylation asymmetric catalysis hydrogen bonds N-ligands palladium
摘要：

Several new ferrocene-derived bidentate N ligands, which contain multiple chiral factors, have been designed and synthesized by a rational combination of oxazoline and pyridine. Their catalytic performances were investigated preliminarily in Pd-catalyzed asymmetric allylic alkylation, and excellent reactivities and enantioselectivities (up to 99% yield and 98% ee) were realized if we used the ligand with a matched chirality. DFT calculations were used to illustrate that an intramolecular hydrogen bond formed between the hydroxyl group and the oxazoline fragment of the ligand contributed to the optimal conformation of the ligand-Pd-allyl complex.
推荐引用方式
GB/T 7714：

Yao Lin,Nie Huifang,Zhang Dongxu, et al. Chiral Ferrocenyl N,N Ligands with Intramolecular Hydrogen Bonds for Highly Enantioselective Allylic Alkylations [J].CHEMCATCHEM,2018,10(4):804-809.
APA：

Yao Lin,Nie Huifang,Zhang Dongxu,Wang Libin,&Zhang Shengyong.(2018).Chiral Ferrocenyl N,N Ligands with Intramolecular Hydrogen Bonds for Highly Enantioselective Allylic Alkylations .CHEMCATCHEM,10(4):804-809.
MLA：

Yao Lin, et al. "Chiral Ferrocenyl N,N Ligands with Intramolecular Hydrogen Bonds for Highly Enantioselective Allylic Alkylations" .CHEMCATCHEM 10,4(2018):804-809.

浏览次数：3  下载次数：0

分享到：

浏览次数：3

下载次数：0

打印次数：0