Optical micromanipulation has become popular for a wide range of applications. In this work, a new type of optical micromanipulation platform, patterned optoelectronic tweezers (p-OET), is introduced. In p-OET devices, the photoconductive layer (that is continuous in a conventional OET device) is patterned, forming regions in which the electrode layer is locally exposed. It is demonstrated that micropatterns in the photoconductive layer are useful for repelling unwanted particles/cells, and also for keeping selected particles/cells in place after turning off the light source, minimizing light-induced heating. To clarify the physical mechanism behind these effects, systematic simulations are carried out, which indicate the existence of strong nonuniform electric fields at the boundary of micropatterns. The simulations are consistent with experimental observations, which are explored for a wide variety of geometries and conditions. It is proposed that the new technique may be useful for myriad applications in the rapidly growing area of optical micromanipulation.
[1]Univ Toronto, Donnelly Ctr Cellular & Biomol Res, Toronto, ON M5S 3E1, Canada;
[2]Univ Toronto, Dept Chem, Toronto, ON M5S 3H6, Canada;
[3]Univ Toronto, Inst Biomat & Biomed Engn, Toronto, ON M5S 3G9, Canada;
[4]Sun Yat Sen Univ, Sch Elect & Informat Technol, State Key Lab Optoelect Mat & Technol, Guangzhou 510275, Guangdong, Peoples R China;
[5]Fudan Univ, Inst Elect Light Sources, Shanghai 200433, Peoples R China;
[6]Univ Toronto, Dept Elect & Comp Engn, Toronto, ON M5S 3G4, Canada;
[7]Univ Toronto, Dept Mat Sci & Engn, Toronto, ON M5S 3E4, Canada;
[8]Univ Bristol, Merchant Venturers Sch Engn, Photon Grp, Bristol BS81UB, Avon, England;
[9]Univ Toronto, Med Design, Toronto, ON M5S 3G9, Canada;
[10]Univ British Columbia, Sch Biomed Engn, Vancouver, BC V6T 1Z3, Canada;
[11]Univ British Columbia, Michael Smith Labs, Vancouver, BC V6T 1Z3, Canada
(8.0+极速模式)