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Arginase-flotillin interaction brings arginase to red blood cell membrane  期刊论文  

  • 编号:
    d76ac3f9-d8c2-4c04-bc0b-ad1ce6495e1f
  • 作者:
    Jiang, Ming; Ding, Yu; Su, Yang; Hu, Xiajian; Li, Jinying; Zhang, Zhihong
  • 语种:
    English
  • 期刊:
    FEBS LETTERS ISSN:1873-3468 2006 年 580 卷 28-29 期 (6561 - 6564) ; DEC 11
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  • 关键词:
  • 摘要:

    Flotillin-1 and arginase are both up-regulated in red blood cell membrane of type 2 diabetic patients. For studying why the soluble arginase can bind to the membrane and whether such binding would modify arginase activity, the arginase1 and related proteins were cloned and expressed. The results showed that flotillin-1 can interact with arginase1, and hence arginase activity was up-regulated by 26.8%. It was estimated that about 61% of arginase1 is bound to the membrane mediated by flotillin-1. The arginase activity in diabetic patients was significantly higher than that of the controls (752.4 +/- 38.5 U/mg protein vs 486.7 +/- 28.7 U/mg protein). (c) 2006 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.

  • 推荐引用方式
    GB/T 7714:
    Jiang Ming,Ding Yu,Su Yang, et al. Arginase-flotillin interaction brings arginase to red blood cell membrane [J].FEBS LETTERS,2006,580(28-29):6561-6564.
  • APA:
    Jiang Ming,Ding Yu,Su Yang,Hu Xiajian,&Zhang Zhihong.(2006).Arginase-flotillin interaction brings arginase to red blood cell membrane .FEBS LETTERS,580(28-29):6561-6564.
  • MLA:
    Jiang Ming, et al. "Arginase-flotillin interaction brings arginase to red blood cell membrane" .FEBS LETTERS 580,28-29(2006):6561-6564.
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