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Establishment of TUSMi005-A, an induced pluripotent stem cell (iPSC) line from a 32-year old Chinese Han patient with Bipolar Disorder (BD)  期刊论文  

  • 编号:
    fe7590b9-2c3a-4551-8ae7-45d04009f5f8
  • 作者:
    Wang, Ying[1,3,4] Fen, Qiang[2] Yu, Hongxiang[1] Qiu, Haixia[5] Ma, Xiquan[2] Lei, Ying[1] Zhao, Jian[1,3]
  • 语种:
    English
  • 期刊:
    STEM CELL RESEARCH ISSN:1873-5061 2018 年 33 卷 (65 - 68) ; DEC
  • 收录:
  • 摘要:

    A 32-year old Bipolar Disorder (BD) male patient donated his Peripheral blood mononuclear cells (PBMC). The non-integrating episomal vector system used to reprogram PBMCs with the human OKSM transcription factors. The pluripotency of transgene-free iPSCs was confirmed by immunocytochemistry for pluripotency markers and by the ability of the iPSCs to differentiate spontaneously into 3 germ layers in vitro. In addition, the iPSC line displayed a normal karyotype. Our model might offer a good platform to further study the pathological mechanisms, to identify early biomarkers, and also for drug testing studies in BD.

  • 推荐引用方式
    GB/T 7714:
    Wang Ying,Fen Qiang,Yu Hongxiang, et al. Establishment of TUSMi005-A, an induced pluripotent stem cell (iPSC) line from a 32-year old Chinese Han patient with Bipolar Disorder (BD) [J].STEM CELL RESEARCH,2018,33:65-68.
  • APA:
    Wang Ying,Fen Qiang,Yu Hongxiang,Qiu Haixia,&Zhao Jian.(2018).Establishment of TUSMi005-A, an induced pluripotent stem cell (iPSC) line from a 32-year old Chinese Han patient with Bipolar Disorder (BD) .STEM CELL RESEARCH,33:65-68.
  • MLA:
    Wang Ying, et al. "Establishment of TUSMi005-A, an induced pluripotent stem cell (iPSC) line from a 32-year old Chinese Han patient with Bipolar Disorder (BD)" .STEM CELL RESEARCH 33(2018):65-68.
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