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The effect of age-related risk factors and comorbidities on white matter injury and repair after ischemic stroke 期刊论文

编号：

ffd2fb52-2ddf-4248-a774-a1ea06b08bdc
作者：

Xu, Mingyue^[1,2,3,4];Wang, Michael M.^[5,6,7];Gao, Yanqin(高艳琴)^[3,4]Keep, Richard F.^[8];Shi, Yejie^[1,2];
语种：

英文
期刊：

NEUROBIOLOGY OF DISEASE ISSN：0969-9961 2019 年 126 卷 (13 - 22) ; JUN
收录：
关键词：

Aging Diffusion tensor imaging Hypertension Inflammation Myelin Stroke White matter
摘要：

White matter injury is a crucial component of human stroke, but it has often been neglected in preclinical studies. Most human stroke is associated with one or more comorbidities, including aging, hypertension, diabetes and metabolic syndrome including hyperlipidemia. The purpose of this review is to examine how age and hypertension impact stroke-induced white matter injury as well as white matter repair in both human stroke and preclinical models. It is essential that comorbidities be examined in preclinical trials as they may impact translatability to the clinic. In addition, understanding how comorbidities impact white matter injury and repair may provide new therapeutic opportunities for patients with those conditions.
推荐引用方式
GB/T 7714：

Xu Mingyue,Wang Michael M.,Gao Yanqin, et al. The effect of age-related risk factors and comorbidities on white matter injury and repair after ischemic stroke [J].NEUROBIOLOGY OF DISEASE,2019,126:13-22.
APA：

Xu Mingyue,Wang Michael M.,Gao Yanqin,Keep Richard F.,&Shi Yejie.(2019).The effect of age-related risk factors and comorbidities on white matter injury and repair after ischemic stroke .NEUROBIOLOGY OF DISEASE,126:13-22.
MLA：

Xu Mingyue, et al. "The effect of age-related risk factors and comorbidities on white matter injury and repair after ischemic stroke" .NEUROBIOLOGY OF DISEASE 126(2019):13-22.
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