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In Vitro Culture of Human Norovirus in the Last 20 Years 期刊论文

编号：

7E30D755DEC07249C40D43BCBE5A0C49
作者：

Cheng, Chao^[1];Cai, Xia(蔡霞)^[2]Li, Jingjing^[1];Zhang, Xiaomeng^[1];Xie, Youhua(谢幼华)^[1]Zhang, Junqi^[1];
语种：

英文
期刊：

BIOMEDICINES ISSN：2227-9059 2024 年 12 卷 11 期 ; NOV
收录：
关键词：

HuNoVs in vitro culture enteroid organoid
摘要：

Human noroviruses (HuNoVs) are the main pathogens that cause acute gastroenteritis and lead to huge economic losses annually. Due to the lack of suitable culture systems, the pathogenesis of HuNoVs and the development of vaccines and drugs have progressed slowly. Although researchers have employed various methods to culture HuNoVs in vitro in the last century, problems relating to the irreducibility, low viral titer, and non-infectiousness of the progeny virus should not be ignored. In 2016, researchers achieved the cultivation and successive passaging of some HuNoV genotypes using human intestinal enteroids, initially demonstrating the potential use of organoids in overcoming this challenge. This paper reviews the efforts made in the last 20 years to culture HuNoVs in vitro and discusses the superiority and limitations of employing human intestinal enteroids/organoids as an in vitro culture model for HuNoVs.
推荐引用方式
GB/T 7714：

Cheng Chao,Cai Xia,Li Jingjing, et al. In Vitro Culture of Human Norovirus in the Last 20 Years [J].BIOMEDICINES,2024,12(11).
APA：

Cheng Chao,Cai Xia,Li Jingjing,Zhang Xiaomeng,&Zhang Junqi.(2024).In Vitro Culture of Human Norovirus in the Last 20 Years .BIOMEDICINES,12(11).
MLA：

Cheng Chao, et al. "In Vitro Culture of Human Norovirus in the Last 20 Years" .BIOMEDICINES 12,11(2024).
入库时间：

2025/2/19 15:39:20
更新时间：

2025/2/21 12:42:40

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