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The Shanghai Aging Study: Study Design, Baseline Characteristics, and Prevalence of Dementia 期刊论文

编号：

b0137e4e-e48c-4f70-b93d-6af1ea61d468
作者：

Ding, Ding(丁玎)#^[1]Zhao, Qianhua(赵倩华)^[1]Guo, Qihao(郭起浩)^[1]Meng, Haijiao(孟海娇)^[1]Wang, Bei(王蓓)^[1]Yu, Peimin(虞培敏)^[1]Luo, Jianfeng(罗剑锋)^[2]Zhou, Yan(周燕)^[1]Yu, Lirong(俞丽蓉)^[1]Zheng, Li^[1];Chu, Shuguang(初曙光)^[3]Mortimer, James A.^[4];Borenstein, Amy R.^[4];Hong, Zhen(洪震)*^[1]
语种：

English
期刊：

NEUROEPIDEMIOLOGY ISSN：0251-5350 2014 年 43 卷 2 期 (114 - 122)
收录：
关键词：

Aging dementia Epidemiological methods Cohort study Mild cognitive impairment Prevalence rate Neuropsychological tests
摘要：

Background: To establish a prospective cohort to enumerate the prevalence, incidence and risk factors for dementia and mild cognitive impairment (MCI) among residents aged >= 60 in an urban community of Shanghai, China. Methods: Participants received clinical evaluations including physical measurements, demographic and lifestyle questionnaires, physical and neurologic examinations, and neuropsychological testing. Urine and blood samples were collected, aliquoted, and stored. DNA was extracted for Apolipoprotein (APOE) genotyping. Diagnoses of dementia and MCI were made using standard criteria via consensus diagnosis. Results: Among 3,141 participants aged >= 60, 1,438 (45.8%) were men. The average age of participants was 72.3 years (SD 8.1), and they had an average of 11.6 years (SD 4.4) of education. The most common chronic disease of participants was hypertension (56.4%). The frequencies of APOE epsilon 2, epsilon 3 and epsilon 4 were 7.9, 82.7 and 9.4%, respectively. We diag-nosed 156 (5.0%, 95% Cl 4.3-5.8%) participants with dementia. The prevalence rates of Alzheimer's disease and vascular dementia were 3.6% (95% Cl 3.0-4.3%) and 0.8% (95% Cl 0.5-1.1%). Conclusions: The Shanghai Aging Study is the first prospective community-based cohort study of cognitive impairment in China, with a comparable study design, procedures, and diagnostic criteria for dementia and MCI to most previous cohort studies in developed countries. (C) 2014 S. Karger AG, Basel.
推荐引用方式
GB/T 7714：

Ding Ding,Zhao Qianhua,Guo Qihao, et al. The Shanghai Aging Study: Study Design, Baseline Characteristics, and Prevalence of Dementia [J].NEUROEPIDEMIOLOGY,2014,43(2):114-122.
APA：

Ding Ding,Zhao Qianhua,Guo Qihao,Meng Haijiao,&Hong Zhen.(2014).The Shanghai Aging Study: Study Design, Baseline Characteristics, and Prevalence of Dementia .NEUROEPIDEMIOLOGY,43(2):114-122.
MLA：

Ding Ding, et al. "The Shanghai Aging Study: Study Design, Baseline Characteristics, and Prevalence of Dementia" .NEUROEPIDEMIOLOGY 43,2(2014):114-122.
入库时间：

2019/5/28 21:47:24
更新时间：

2019/5/28 21:47:24

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